MED15 and TRIM11

Number of citations of the paper that reports this interaction (PubMedID 16904669)
17

Data Source:
HPRD (in vivo)

		MED15	TRIM11
Description		mediator complex subunit 15	tripartite motif containing 11
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Membrane Mediator Complex	Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Transcription Coregulator Activity Protein Binding	Protein Binding Transcription Factor Binding Zinc Ion Binding Protein Domain Specific Binding Ubiquitin Protein Ligase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Stem Cell Population Maintenance	Protein Ubiquitination Negative Regulation Of Viral Transcription Innate Immune Response Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Viral Entry Into Host Cell Positive Regulation Of Viral Entry Into Host Cell Negative Regulation Of Neurogenesis Defense Response To Virus Negative Regulation Of Viral Release From Host Cell
Pathways		PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Lung function (FEV1/FVC) ( 30061609)	Hip circumference (psychosocial stress interaction) ( 25271088) Non-Richardson's syndrome vs Richardson's syndrome in progressive supranuclear palsy ( 30066433)
Interacting Genes		12 interacting genes: ATP5F1C ATXN1 CTDP1 FHL3 MED25 MLLT6 PLSCR1 RELA SMAD2 SMAD3 TRIM11 UBC	7 interacting genes: MED15 PAX6 RNF126 TRIM27 TRIM29 TRIM35 USP14
Entrez ID		51586	81559
HPRD ID		12117	07429
Ensembl ID		ENSG00000099917	ENSG00000154370
Uniprot IDs		B7Z2H7 G3V1P5 Q6PKB8 Q96RN5	Q96F44
PDB IDs		2GUT
Enriched GO Terms of Interacting Partners?
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