PHF7 and RNF34

Number of citations of the paper that reports this interaction (PubMedID 22493164)
5

Data Source:
BioGRID (two hybrid)

		PHF7	RNF34
Description		PHD finger protein 7	ring finger protein 34
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Golgi Apparatus Cytosol Plasma Membrane Nuclear Speck	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Endomembrane System Nuclear Body Nuclear Speck
	Molecular Function	Protein Binding Metal Ion Binding	P53 Binding Protein Binding Ubiquitin Protein Ligase Binding Metal Ion Binding Ubiquitin Protein Ligase Activity Phosphatidylinositol Phosphate Binding
	Biological Process		Ubiquitin-dependent Protein Catabolic Process Apoptotic Process Protein Ubiquitination Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Response To Cold Protein K48-linked Ubiquitination Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Oxygen Metabolic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Execution Phase Of Apoptosis
Pathways			Regulation of TP53 Degradation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972) Parkinson's disease ( 28892059) Schizophrenia ( 23974872)
Interacting Genes		16 interacting genes: APP ARIH2 DTX3L H3-4 IKBKG MAGEF1 MDM2 RNF111 RNF14 RNF34 SRPK1 TRIM26 TRIM41 UBE2D4 USP1 USP15	9 interacting genes: APP APPBP2 DNAJA3 NOD1 PHF7 TRIM23 UBE2D2 UBE2F UBE2H
Entrez ID		51533	80196
HPRD ID		15127	10509
Ensembl ID		ENSG00000010318	ENSG00000170633
Uniprot IDs		A0A024R336 A8K856 Q9BWX1	A0A087WTM5 Q969K3
PDB IDs
Enriched GO Terms of Interacting Partners?
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