UBE2J1 and DIO2

Number of citations of the paper that reports this interaction (PubMedID 12933904)
22

Data Source:
BioGRID (pull down)

		UBE2J1	DIO2
Description		ubiquitin conjugating enzyme E2 J1	iodothyronine deiodinase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane	Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	ATP Binding Ubiquitin Protein Ligase Binding Ubiquitin Conjugating Enzyme Activity	Thyroxine 5'-deiodinase Activity Selenium Binding Ubiquitin Protein Ligase Binding Thyroxine 5-deiodinase Activity
	Biological Process	Spermatid Development Protein Ubiquitination Protein N-linked Glycosylation Via Asparagine Ubiquitin-dependent ERAD Pathway Regulation Of Tumor Necrosis Factor Biosynthetic Process Negative Regulation Of Retrograde Protein Transport, ER To Cytosol	Selenocysteine Incorporation Thyroid Hormone Generation Thyroid Hormone Metabolic Process Thyroid Hormone Catabolic Process Hormone Biosynthetic Process Brown Fat Cell Differentiation Oxidation-reduction Process Positive Regulation Of Cold-induced Thermogenesis
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Regulation of thyroid hormone activity
Drugs
Diseases
GWAS			Free thyroxine concentration ( 30367059) Metabolite levels ( 23823483) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Rosacea symptom severity ( 29771307)
Interacting Genes		14 interacting genes: AQP2 BIRC2 BRCA1 CREB3 DIO2 LRSAM1 MAPKAPK2 PJA2 PRKN RNF2 TOPORS TRIM27 TRIM63 UBA1	6 interacting genes: MARCHF6 UBE2G1 UBE2J1 USP20 USP33 WSB1
Entrez ID		51465	1734
HPRD ID		15599	09027
Ensembl ID		ENSG00000198833	ENSG00000211448
Uniprot IDs		Q9Y385	A8K845 Q92813
PDB IDs
Enriched GO Terms of Interacting Partners?
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