WAC and SYTL5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		WAC	SYTL5
Description		WW domain containing adaptor with coiled-coil	synaptotagmin like 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Nuclear Speck	Plasma Membrane Membrane Exocytic Vesicle
	Molecular Function	RNA Polymerase II Complex Binding Chromatin Binding Protein Binding	Protein Binding Phospholipid Binding Rab GTPase Binding Neurexin Family Protein Binding Metal Ion Binding
	Biological Process	Cellular Response To DNA Damage Stimulus Histone Monoubiquitination Positive Regulation Of Macroautophagy Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process G1 DNA Damage Checkpoint Positive Regulation Of Transcription, DNA-templated Histone H2B Conserved C-terminal Lysine Ubiquitination	Intracellular Protein Transport Exocytosis
Pathways		E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30224653) Intraocular pressure ( 29617998) Multiple myeloma ( 27363682)	Anorexia nervosa ( 23568457) Erectile dysfunction and prostate cancer treatment ( 20932654)
Interacting Genes		20 interacting genes: AKAP9 APP CRKL DYDC1 KLC3 KRT15 LNX1 MOBP MTUS2 NDE1 NFE2L2 POLR2A SYTL5 TRAF1 TRAF3IP1 TRAF3IP3 UBQLN4 VCP VCPIP1 ZDHHC17	6 interacting genes: CEP70 RAB27A RAB27B RAB3A RAB6A WAC
Entrez ID		51322	94122
HPRD ID		18291	06736
Ensembl ID		ENSG00000095787	ENSG00000147041
Uniprot IDs		Q9BTA9	Q8TDW5
PDB IDs
Enriched GO Terms of Interacting Partners?
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