PCCB and PCCA

Number of citations of the paper that reports this interaction (PubMedID 11749052)
6

Data Source:
HPRD (two hybrid)

		PCCB	PCCA
Description		propionyl-CoA carboxylase subunit beta	propionyl-CoA carboxylase subunit alpha
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Cytosol	Mitochondrion Mitochondrial Matrix Cytosol
	Molecular Function	Propionyl-CoA Carboxylase Activity Protein Binding ATP Binding	Propionyl-CoA Carboxylase Activity Protein Binding ATP Binding Biotin Binding Enzyme Binding Metal Ion Binding
	Biological Process	Biotin Metabolic Process Short-chain Fatty Acid Catabolic Process	Biotin Metabolic Process Short-chain Fatty Acid Catabolic Process
Pathways		Biotin transport and metabolism Defective HLCS causes multiple carboxylase deficiency Propionyl-CoA catabolism	Biotin transport and metabolism Defective HLCS causes multiple carboxylase deficiency Propionyl-CoA catabolism
Drugs		Biotin L-Valine	Biotin
Diseases		Propionic acidemia	Propionic acidemia
GWAS		Alanine transaminase levels ( 29403010) Autism spectrum disorder or schizophrenia ( 28540026) Fibrinogen ( 20031576 23969696) Fibrinogen levels ( 28107422) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) Height ( 28552196 20881960) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) Metabolic syndrome ( 31589552) Non-word reading ( 30741946) Schizophrenia ( 28991256 25056061 29483656) Systolic blood pressure ( 30224653) Total bilirubin levels ( 29403010) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Triglyceride levels x long total sleep time interaction (2df test) ( 31719535)	Chromosomal aberration frequency (chromatid type) in genotoxic compound exposure ( 31586183) Corpus callosum anterior volume ( 31530798) Metabolite levels ( 23823483) Myopia ( 27182965) Refractive error ( 23396134) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking initiation (ever regular vs never regular) ( 30679032) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		2 interacting genes: MTDH PCCA	3 interacting genes: ERRFI1 PCCB PJA1
Entrez ID		5096	5095
HPRD ID		01982	01981
Ensembl ID		ENSG00000114054	ENSG00000175198
Uniprot IDs		P05166	P05165
PDB IDs			2CQY 2JKU
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?