TBX22 and VENTX

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TBX22	VENTX
Description		T-box transcription factor 22	VENT homeobox
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus	Nuclear Chromatin Nucleus
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Activating Transcription Factor Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Cell Fate Specification Regulation Of Transcription, DNA-templated Multicellular Organism Development Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Positive Regulation Of Transcription By RNA Polymerase II
Pathways			Senescence-Associated Secretory Phenotype (SASP) Transcriptional Regulation by VENTX
Drugs
Diseases		Isolated orofacial clefts, including: Cleft lip with or without cleft palate; Cleft palate Cleft palate with ankyloglossia
GWAS		Nose size ( 27182965)
Interacting Genes		2 interacting genes: APP VENTX	9 interacting genes: C1orf94 DAB1 IRF9 KRTAP12-2 KRTAP12-4 RBPMS TBX15 TBX22 TLE2
Entrez ID		50945	27287
HPRD ID		02253	06197
Ensembl ID		ENSG00000122145	ENSG00000151650
Uniprot IDs		B3KUL8 Q9Y458	O95231
PDB IDs
Enriched GO Terms of Interacting Partners?
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