PRKN and SNCAIP

  • Number of citations of the paper that reports this interaction (PubMedID 15894486)
  • 12
  • Data Source:
  • BioGRID (two hybrid)

PRKN

SNCAIP

Description parkin RBR E3 ubiquitin protein ligase synuclein alpha interacting protein
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Chronic kidney disease (end stage renal disease vs. normal eGFR) in type 1 diabetes ( 31537649)
  • Delirium ( 29631748)
  • Depressive symptoms x independent stressful life events interaction (2df test) ( 30718454)
  • Event free survival in diffuse large B-cell lymphoma treated with immunochemotherapy ( 26460308)
  • Heart rate increase in response to exercise ( 29497042)
  • Heart rate response to recovery post exercise (50 sec) ( 29497042)
  • Mood disorder and prion disease ( 25897833)
  • Response to paclitaxel in ovarian cancer (Caspase 3/7 EC50) ( 27047539)
Interacting Genes 113 interacting genes: ADRM1 AIMP2 ARRB1 ARRB2 ATXN3 BAG5 BCL2L1 CASK CASP1 CASP8 CCNB1 CCND1 CDC34 CDK5 CHPF COMMD1 CRX CUL1 DLG1 DLX2 DNM1L DYRK1A EPS15 FAF1 FBP1 FBXO7 FBXW7 GPR37 GRIN2B HDAC6 HEXD HSD17B10 IKBKG MEOX1 MEOX2 MFN1 MFN2 NDUFA4L2 NEK2 PAFAH1B2 PDCD2 PICK1 PKM PLK1 PSMA1 PSMA7 PSMC1 PSMC2 PSMC5 PSMD4 PTPN5 PTTG1 RAB7A RAC1 RAD1 RAD23A RANBP2 RBCK1 REL RGS2 RGS3 RHOT1 RHOT2 SEPTIN4 SEPTIN5 SIM2 SNCA SNCAIP STUB1 SUMO1 SYT11 TCF4 TENT5C TOMM40 TOMM70 TP53 TRIP13 TUBA4A TUBB UBASH3A UBASH3B UBB UBC UBE2A UBE2B UBE2C UBE2D1 UBE2D2 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2G1 UBE2G2 UBE2H UBE2J1 UBE2J2 UBE2K UBE2L3 UBE2L6 UBE2M UBE2N UBE2O UBE2R2 UBE2S UBE2T UBE2V1 UBE2Z UCHL1 USP30 VDAC1 YWHAH ZNF746 19 interacting genes: AGXT C11orf58 GET4 GSK3B NUB1 NUDT21 PIN1 PINK1 PPHLN1 PRKN PTN RNF19A SEPTIN4 SH2D3C SIAH1 SIAH2 SNCA TLE5 UBB
Entrez ID 5071 9627
HPRD ID 03967 04804
Ensembl ID ENSG00000185345 ENSG00000064692
Uniprot IDs O60260 X5DR79 B7Z616 B7Z995 Q6L981 Q6L983 Q9Y6H5
PDB IDs 1IYF 2JMO 4BM9 4I1F 4I1H 5C1Z 5C23 5C9V 5N2W 5N38 5TR5 6GLC 6HUE 6N13 2KES
Enriched GO Terms of Interacting Partners?
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