PAK2 and ARHGEF7

  • Number of citations of the paper that reports this interaction (PubMedID 12226077)
  • 41
  • Data Source:
  • HPRD (in vivo, in vitro)

PAK2

ARHGEF7

Description p21 (RAC1) activated kinase 2 Rho guanine nucleotide exchange factor 7
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Bilirubin levels ( 19414484)
  • Choroid plexus volume ( 31530798)
  • Fasting insulin (dietary factor interaction) ( 24204828)
  • Homeostasis model assessment of insulin resistance (dietary factor interaction) ( 24204828)
  • Macular thickness ( 30535121)
  • Menarche (age at onset) ( 21102462)
  • Menopause (age at onset) ( 19448619)
  • Skin aging measurement ( 31522824)
Interacting Genes 51 interacting genes: ABI1 ABI3 ABL1 APP ARHGAP10 ARHGEF6 ARHGEF7 BRAF CASP3 CDC42 DOCK2 DST EIF4B EIF4G1 EP300 FYN GRB2 H4C6 HCK LCK LIMK1 LYN MAPK1 MAPK3 MKNK1 MYC MYL2 MYLK NCK1 NPHP1 PACSIN3 PPM1A RAC1 RAC2 RAF1 RIOK3 RPS6 SH3GL2 SH3KBP1 SH3PXD2A SH3RF1 SH3RF3 SNX33 SNX9 SORBS1 SORBS2 SORBS3 SRC SYN1 VIM YES1 33 interacting genes: ADAM15 ARHGEF6 CALM1 CBLB CD244 CDC42 EGFR ERBIN GIT1 GIT2 HSPB1 ITCH LRRK2 MEOX2 NCK1 NCKIPSD NOX1 PAK1 PAK2 PAK3 PPM1E PPM1F PRKCG PXN RAC1 SCRIB SH2D1A SHANK1 SHANK2 TGFBR2 TUBB3 WAS YWHAG
Entrez ID 5062 8874
HPRD ID 05428 05688
Ensembl ID ENSG00000180370 ENSG00000102606
Uniprot IDs A8K5M4 Q13177 A0A024RDY9 B7Z344 B7Z6G2 E9PDQ5 Q14155 Q5W9H1
PDB IDs 3PCS 1BY1 1ZSG 2L3G 5SXP
Enriched GO Terms of Interacting Partners?
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