SERPINE1 and MMP3

  • Number of citations of the paper that reports this interaction (PubMedID 10967118)
  • 16
  • Data Source:
  • HPRD (in vitro)

SERPINE1

MMP3

Description serpin family E member 1 matrix metallopeptidase 3
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood protein levels ( 30072576)
  • Nonunion in individuals with fractures ( 30680360)
  • Plasma plasminogen activator levels ( 24578379)
  • Plasminogen activator inhibitor type 1 levels (PAI-1) ( 22990020)
  • Alzheimer's disease ( 22832961)
  • Blood protein levels ( 30072576 28240269)
  • Blood protein levels in cardiovascular risk ( 28369058)
  • Cerebrospinal fluid levels of Alzheimer's disease-related proteins ( 25340798)
  • Peripheral artery disease ( 31285632)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)
Interacting Genes 20 interacting genes: ACTN4 ELANE F2 IGFBP5 KLK2 KRT18 LMNA LRP1 LRP1B LRP2 MMP3 ORM1 PLAT PLAU PLG SGTA SGTB UBQLN1 UBQLN4 VTN 19 interacting genes: ACAN BCAN CCL13 CCL2 CCL7 CCL8 DCN HAPLN1 IGFBP3 MEOX2 MMP14 PLG SERPINE1 SPOCK1 SPOCK3 SPP1 TIMP1 TIMP3 TNFSF11
Entrez ID 5054 4314
HPRD ID 01418 01703
Ensembl ID ENSG00000106366 ENSG00000149968
Uniprot IDs A0A024QYT5 P05121 P08254
PDB IDs 1A7C 1B3K 1C5G 1DB2 1DVM 1DVN 1LJ5 1OC0 3CVM 3EOX 3PB1 3Q02 3Q03 3R4L 3UT3 4AQH 4G8O 4G8R 4IC0 5BRR 5ZLZ 6I8S 9PAI 1B3D 1B8Y 1BIW 1BM6 1BQO 1C3I 1C8T 1CAQ 1CIZ 1CQR 1D5J 1D7X 1D8F 1D8M 1G05 1G49 1G4K 1HFS 1HY7 1M1W 1OO9 1QIA 1QIC 1SLM 1SLN 1UEA 1UMS 1UMT 1USN 2D1O 2JNP 2JT5 2JT6 2SRT 2USN 3OHL 3OHO 3USN 4DPE 4G9L 4JA1 6MAV 6N9D
Enriched GO Terms of Interacting Partners?
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