PA2G4 and HSPA4

Number of citations of the paper that reports this interaction (PubMedID 27464702)
1

Data Source:
BioGRID (far western blotting)

		PA2G4	HSPA4
Description		proliferation-associated 2G4	heat shock protein family A (Hsp70) member 4
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Nucleolus Cytoplasm Membrane Azurophil Granule Lumen Extracellular Exosome	Nucleus Cytosol Extracellular Exosome
	Molecular Function	Nucleic Acid Binding DNA Binding DNA-binding Transcription Factor Activity RNA Binding Protein Binding Ubiquitin Protein Ligase Binding	Protein Binding ATP Binding
	Biological Process	RRNA Processing Regulation Of Translation Negative Regulation Of Apoptotic Process Neutrophil Degranulation Positive Regulation Of Cell Differentiation Negative Regulation Of Transcription, DNA-templated	Response To Unfolded Protein Protein Import Into Mitochondrial Outer Membrane Chaperone-mediated Protein Complex Assembly
Pathways		Neutrophil degranulation	Regulation of HSF1-mediated heat shock response
Drugs			Phenethyl Isothiocyanate
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Anorexia nervosa ( 28494655) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Vitiligo ( 22951725)	Breast cancer ( 29059683) Chronic obstructive pulmonary disease ( 30804561) Diastolic blood pressure ( 30224653) Eyebrow thickness ( 26926045) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Heel bone mineral density ( 30598549) Metabolite levels ( 23823483) Reticulocyte fraction of red cells ( 27863252) Triglyceride levels ( 30698716) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
Interacting Genes		21 interacting genes: AR ATR ERBB3 ESR1 EXOSC5 HDAC2 HMGA1 HMGA2 HSPA4 IKBKG LIG4 MTOR PRKCA PRKCB PRKCG RB1 RNF20 SIN3A STUB1 SUMO4 TERF1	65 interacting genes: ABCC2 AGTRAP APPBP2 BAG1 BAG2 BAG5 BRMS1 CALM1 CD40 CDC73 CDKN2A CSNK1A1 CSNK2A1 DDIT4 DNAJB1 DNAJB2 DUSP1 EGFR ESR1 FANCC FES FKBP4 GATA1 GRPEL2 GSK3B GZMA HAP1 HDAC3 HNRNPD HSPB1 HSPBP1 IKBKG KPNA2 KRT18 MUC1 NAA10 NFKB1 NR3C2 OLR1 PA2G4 PHLDA1 PPP1CA PRKACA PRKCB PRKCD PRKCG PRSS23 PSMD10 RAF1 RAP1A REL RELA SGTA SIRPA SMAD3 ST13 STUB1 SUGT1 TERT TOMM40 TRAF6 TRIM32 TTC1 UBE2L3 UBE3A
Entrez ID		5036	3308
HPRD ID		03685	09025
Ensembl ID		ENSG00000170515	ENSG00000170606
Uniprot IDs		A0A024RB85 Q9UQ80	P34932
PDB IDs		2Q8K 3J2I 6CHT
Enriched GO Terms of Interacting Partners?
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