OTX2 and DMBX1

Number of citations of the paper that reports this interaction (PubMedID 15890343)
4

Data Source:
HPRD (in vitro)

		OTX2	DMBX1
Description		orthodenticle homeobox 2	diencephalon/mesencephalon homeobox 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Growth Cone Protein-containing Complex	Nuclear Chromatin Transcription Factor Complex
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Eukaryotic Initiation Factor 4E Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Identical Protein Binding Sequence-specific DNA Binding
	Biological Process	Axon Guidance Regulation Of Smoothened Signaling Pathway Forebrain Development Midbrain Development Positive Regulation Of Embryonic Development Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Protein-containing Complex Assembly Dopaminergic Neuron Differentiation Primitive Streak Formation Positive Regulation Of Gastrulation	Negative Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Brain Development Adult Feeding Behavior Adult Locomotory Behavior Negative Regulation Of Transcription, DNA-templated Developmental Growth
Pathways
Drugs
Diseases		Anophthalmia and microphthalmia (A/M) Septo-optic dysplasia
GWAS		Alcohol consumption ( 31358974) Alcohol consumption (drinks per week) ( 30643258) Chronotype ( 30696823) Moderate-to-late spontaneous preterm birth ( 31194736)	Blood metabolite levels ( 24816252) Body mass index ( 26426971) Monobrow ( 27182965) Serum uric acid levels in response to allopurinol in gout ( 25676789) Urate levels in obese individuals ( 25811787)
Interacting Genes		10 interacting genes: APP ATXN1 CDK4 DMBX1 FOXA2 LHX1 MITF SMARCB1 TLE4 ZDHHC17	2 interacting genes: OTX2 UBC
Entrez ID		5015	127343
HPRD ID		07190	07593
Ensembl ID		ENSG00000165588	ENSG00000197587
Uniprot IDs		F1T0C9 F1T0D0 F1T0D1 P32243	Q8NFW5
PDB IDs
Enriched GO Terms of Interacting Partners?
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