NRF1 and POGZ

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		NRF1	POGZ
Description		nuclear respiratory factor 1	pogo transposable element derived with ZNF domain
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Extracellular Exosome	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding RNA Polymerase II Core Promoter Sequence-specific DNA Binding Core Promoter Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Protein Homodimerization Activity	Protein Binding Metal Ion Binding
	Biological Process	Generation Of Precursor Metabolites And Energy Regulation Of Transcription By RNA Polymerase II Mitochondrion Organization Positive Regulation Of Transcription By RNA Polymerase II	Mitotic Sister Chromatid Cohesion Regulation Of Gene Expression Cell Division Kinetochore Assembly
Pathways		PPARA activates gene expression Transcriptional activation of mitochondrial biogenesis Transcriptional activation of mitochondrial biogenesis
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Obesity-related traits ( 23251661) Platelet count ( 27863252) Plateletcrit ( 27863252) Red cell distribution width ( 28957414) Response to antidepressants and depression ( 27622933)	Blood trace element (Cu levels) ( 23720494) Body mass index ( 26426971) Pulse pressure ( 30578418)
Interacting Genes		13 interacting genes: CSNK2A1 DYNLL1 FHL2 LHX4 MAFF PARP1 PLXDC1 POGZ PPARGC1A PPRC1 SIAH2 SP4 TRAF2	22 interacting genes: APP BANP CDK6 CREB1 DAB1 DAZAP2 GABPB1 H3-4 HGS NFYA NFYC NRF1 POU2F1 PRR20A QRICH1 RBPMS SP1 SUMO2 UBAP2L VAV2 ZBTB24 ZXDC
Entrez ID		4899	23126
HPRD ID		02930	11445
Ensembl ID		ENSG00000106459	ENSG00000143442
Uniprot IDs		A0A024R770 A0A024R774 Q16656	Q7Z3K3
PDB IDs			2E72 2N3A 6EMP
Enriched GO Terms of Interacting Partners?
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