NRCAM and MAGI3

Number of citations of the paper that reports this interaction (PubMedID 12421765)
39

Data Source:
HPRD (two hybrid)

		NRCAM	MAGI3
Description		neuronal cell adhesion molecule	membrane associated guanylate kinase, WW and PDZ domain containing 3
Image
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Neuron Projection Axon Initial Segment Glutamatergic Synapse Integral Component Of Postsynaptic Density Membrane	Nucleus Cytoplasm Plasma Membrane Cell-cell Junction Bicellular Tight Junction Membrane Cell Junction
	Molecular Function	Protein Binding Ankyrin Binding Protein Binding Involved In Heterotypic Cell-cell Adhesion	Guanylate Kinase Activity Protein Binding ATP Binding Molecular Adaptor Activity
	Biological Process	Angiogenesis Neuron Migration Axonogenesis Axonal Fasciculation Synapse Assembly Central Nervous System Development Protein Localization Neuronal Action Potential Propagation Regulation Of Axon Extension Retinal Ganglion Cell Axon Guidance Heterotypic Cell-cell Adhesion Clustering Of Voltage-gated Sodium Channels Positive Regulation Of Neuron Differentiation Cell-cell Adhesion Regulation Of Postsynapse Organization	Apoptotic Process Signal Transduction Viral Process Intracellular Signal Transduction GMP Metabolic Process Regulation Of JNK Cascade GDP Metabolic Process
Pathways		Interaction between L1 and Ankyrins NrCAM interactions Neurofascin interactions
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Coffee consumption ( 21876539) Diastolic blood pressure ( 27841878) Femoral neck bone geometry and menarche (age at onset) ( 23593202) Systolic blood pressure ( 27841878) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) White matter hyperintensities in ischemic stroke ( 26674333) White matter hyperintensity burden ( 25663218)	Alopecia areata ( 25608926) Bacteremia ( 27236921) Bulimia nervosa ( 23568457) Cerebrospinal fluid clusterin levels ( 26545630) Cognitive decline rate in late mild cognitive impairment ( 26252872) Crohn's disease ( 28067908) Gut microbiota (bacterial taxa) ( 27694959) Obesity-related traits ( 23251661) Type 1 diabetes and autoimmune thyroid diseases ( 25936594)
Interacting Genes		9 interacting genes: ANK2 CNTN2 ELOC HSPA12A LNX1 MACF1 MAGI3 NFASC PTPRB	16 interacting genes: ADGRB1 ADRB1 CRHR1 DSCAML1 FZD4 FZD7 GRIN2B LATS1 NRCAM PLXNB3 PTEN PTPRB RPS6KA1 TGFA TNK2 VANGL2
Entrez ID		4897	260425
HPRD ID		07207	11290
Ensembl ID		ENSG00000091129	ENSG00000081026
Uniprot IDs		B7Z670 C9JYY6 Q14CA1 Q92823	Q5TCQ9
PDB IDs		1UEN 1UEY	3SOE
Enriched GO Terms of Interacting Partners?
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