NPAS2 and RASSF7

Number of citations of the paper that reports this interaction (PubMedID 24722188)
51

Data Source:
BioGRID (two hybrid)

		NPAS2	RASSF7
Description		neuronal PAS domain protein 2	Ras association domain family member 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Cytosol	Cytoplasm Centriolar Satellite
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding Protein Dimerization Activity Hsp90 Protein Binding	Protein Binding
	Biological Process	Cellular Response To DNA Damage Stimulus Central Nervous System Development Circadian Rhythm Regulation Of Lipid Metabolic Process Circadian Regulation Of Gene Expression Response To Drug Positive Regulation Of DNA Repair Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Response To Redox State Negative Regulation Of Cell Death Positive Regulation Of Behavioral Fear Response Regulation Of Response To DNA Damage Stimulus	Apoptotic Process Signal Transduction Regulation Of Microtubule Cytoskeleton Organization
Pathways		BMAL1:CLOCK,NPAS2 activates circadian gene expression BMAL1:CLOCK,NPAS2 activates circadian gene expression PPARA activates gene expression PPARA activates gene expression Circadian Clock Circadian Clock
Drugs
Diseases
GWAS		Chronotype ( 30696823) Creutzfeldt-Jakob disease (variant) ( 22137330) Educational attainment ( 25201988) Intraocular pressure ( 31798171 31959993 30054594) Intraocular pressure and central corneal thickness (multi-trait analysis) ( 31798171) Metabolite levels ( 23823483) Pulse pressure ( 27841878)	Systemic lupus erythematosus ( 26502338)
Interacting Genes		24 interacting genes: ARNT2 ARNTL CLOCK CREBBP CRX CRY1 CRY2 CSNK2B DELEC1 EFS EP300 HESX1 HGS HSP90AA1 KAT2B NCOA3 RARA RASSF7 RHOXF1 RORC RPL6 RXRA TRAF4 ZSCAN1	5 interacting genes: CHMP1B DISC1 NCK2 NPAS2 SNAP29
Entrez ID		4862	8045
HPRD ID		09137	00878
Ensembl ID		ENSG00000170485	ENSG00000099849
Uniprot IDs		A2I2P5 Q99743	A0A024RCE4 Q02833
PDB IDs
Enriched GO Terms of Interacting Partners?
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