ATOX1 and ATP7B

Number of citations of the paper that reports this interaction (PubMedID 10557326)
65

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		ATOX1	ATP7B
Description		antioxidant 1 copper chaperone	ATPase copper transporting beta
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GO Annotations	Cellular Component	Cell Cytosol	Golgi Membrane Cell Mitochondrion Late Endosome Golgi Apparatus Trans-Golgi Network Integral Component Of Plasma Membrane Membrane Basolateral Plasma Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Copper Ion Binding Protein Binding Metallochaperone Activity Copper Chaperone Activity Copper-dependent Protein Binding ATPase Binding	Copper Ion Transmembrane Transporter Activity Copper Ion Binding Protein Binding ATP Binding Copper-transporting ATPase Activity
	Biological Process	Copper Ion Transport Cellular Copper Ion Homeostasis Response To Oxidative Stress Negative Regulation Of Apoptotic Process Copper Ion Export	Copper Ion Transport Cellular Copper Ion Homeostasis Cellular Zinc Ion Homeostasis Lactation Copper Ion Import Protein Maturation By Copper Ion Transfer Ion Transmembrane Transport Response To Copper Ion Sequestering Of Calcium Ion Copper Ion Export Divalent Inorganic Cation Transport
Pathways		Detoxification of Reactive Oxygen Species Ion influx/efflux at host-pathogen interface	Ion transport by P-type ATPases
Drugs		Cisplatin Sucrose Benzamidine
Diseases			Wilson disease; Hepatolenticular degeneration
GWAS		Creatinine levels ( 29403010) Glomerular filtration rate ( 29403010) Systolic blood pressure change trajectories ( 27980656)	Clostridium difficile infection in multiple myeloma ( 29594489) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		6 interacting genes: ATP7A ATP7B CFAP410 FAM118A FKBP4 GGPS1	4 interacting genes: ATOX1 DCTN4 HP ZBTB16
Entrez ID		475	540
HPRD ID		03779	06050
Ensembl ID		ENSG00000177556	ENSG00000123191
Uniprot IDs		O00244	A0A024RDX3 B7ZLR3 B7ZLR4 E7ET55 P35670
PDB IDs		1FE0 1FE4 1FEE 1TL4 1TL5 2K1R 2LQ9 3CJK 3IWL 3IWX 4QOT 4YDX 4YEA 5F0W 5T7L	2ARF 2EW9 2KOY 2LQB 2N7Y 2ROP 6A71 6A72
Enriched GO Terms of Interacting Partners?
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