NDUFS3 and RASL10B

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		NDUFS3	RASL10B
Description		NADH:ubiquinone oxidoreductase core subunit S3	RAS like family 10 member B
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Respiratory Chain Complex I Mitochondrial Matrix Nuclear Body Mitochondrial Membrane	Plasma Membrane
	Molecular Function	NADH Dehydrogenase Activity Protein Binding NADH Dehydrogenase (ubiquinone) Activity Electron Transfer Activity	GTPase Activity GTP Binding
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Substantia Nigra Development Negative Regulation Of Cell Growth Mitochondrial Respiratory Chain Complex I Assembly Reactive Oxygen Species Metabolic Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway	Regulation Of Systemic Arterial Blood Pressure By Atrial Natriuretic Peptide Signal Transduction Positive Regulation Of Peptide Hormone Secretion
Pathways		Respiratory electron transport Complex I biogenesis
Drugs		NADH
Diseases		Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		Alcohol use disorder (total score) ( 30336701) Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Bipolar disorder ( 31043756) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 20935630) Height ( 28552196) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Mood instability ( 31168069) Neuroticism ( 29255261) Sleep duration (short sleep) ( 30846698)	Cerebrospinal AB1-42 levels in normal cognition ( 29274321)
Interacting Genes		2 interacting genes: GZMA RASL10B	10 interacting genes: AKT1 APP BAG4 FGFR2 FGFR4 NDUFS3 NEDD4L PARP1 PAX2 TSG101
Entrez ID		4722	91608
HPRD ID		10355	15215
Ensembl ID		ENSG00000213619	ENSG00000270885
Uniprot IDs		O75489	Q96S79
PDB IDs		5XTB 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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