NEB and TMOD1

Number of citations of the paper that reports this interaction (PubMedID 11016930)
44

Data Source:
HPRD (in vitro, in vivo)

		NEB	TMOD1
Description		nebulin	tropomodulin 1
Image
GO Annotations	Cellular Component	Cytosol Actin Cytoskeleton Z Disc Extracellular Exosome	Cytosol Cytoskeleton Striated Muscle Thin Filament Actin Filament COP9 Signalosome Membrane Myofibril Sarcomere Cortical Cytoskeleton
	Molecular Function	Protein Binding Structural Constituent Of Muscle Actin Filament Binding	Actin Binding Tropomyosin Binding Actin Filament Binding
	Biological Process	Muscle Organ Development Somatic Muscle Development Muscle Filament Sliding Regulation Of Actin Filament Length Muscle Fiber Development Cardiac Muscle Thin Filament Assembly	Muscle Contraction Actin Filament Organization Adult Locomotory Behavior Muscle Filament Sliding Myofibril Assembly Pointed-end Actin Filament Capping Lens Fiber Cell Development
Pathways		Striated Muscle Contraction	Striated Muscle Contraction
Drugs
Diseases		Distal muscular dystrophies, including: Welander distal myopathy (WDM); Tibial muscular dystrophy (TMD); Nonaka distal myopathy with rimmed vacuoles (DMRV); Miyoshi myopathy (MM); Laing myopathy (MPD1); Distal nebulin myopathy (DNM); Distal desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Distal myotilinopathy (MFM3); Distal zaspopathy (MFM4); Distal myopathy 3 (MPD2, VCPDM) Nemaline myopathy
GWAS		Asparaginase-induced acute pancreatitis in acute lymphoblastic leukemia (onset time) ( 27114598) Creatine kinase levels ( 29403010) Estimated glomerular filtration rate ( 31152163 31451708) Letter-number span reordering ( 31596458) Rapid automised naming of letters ( 30741946) Response to cognitive-behavioural therapy in anxiety disorder ( 26989097) Squamous cell lung carcinoma ( 28604730)	Barrett's esophagus ( 27527254) Barrett's esophagus or Esophageal adenocarcinoma ( 27527254) Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging) ( 26252872) Intracranial aneurysm ( 30823506) Obesity-related traits ( 23251661) Thyroid cancer (Papillary, radiation-related) ( 20350937) Zinc levels ( 26025379)
Interacting Genes		18 interacting genes: ABI1 ACTG2 ACTN4 APC CALM1 DES KLHL41 MTDH MYPN TMOD1 TMOD4 TPM1 TPM2 TRIM55 TRIM63 TTN XIRP1 XIRP2	4 interacting genes: NEB PRKAA2 TMSB10 TPM3
Entrez ID		4703	7111
HPRD ID		01196	01838
Ensembl ID		ENSG00000183091	ENSG00000136842
Uniprot IDs		P20929 Q05C45 Q96MF8	P28289
PDB IDs		1ARK 1NEB	4PKG 4PKH 4PKI 4Z8G 4Z94
Enriched GO Terms of Interacting Partners?
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