ATF4 and HK3

  • Number of citations of the paper that reports this interaction (PubMedID 21988832)
  • 75
  • Data Source:
  • BioGRID (two hybrid)

ATF4

HK3

Description activating transcription factor 4 hexokinase 3
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Inflammatory bowel disease ( 23128233)
  • Uterine fibroids ( 30194396)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes 69 interacting genes: APH1A APP ASB7 ATF2 ATF3 BATF BATF2 BATF3 BFSP2 BTRC CCDC106 CEBPA CEBPB CEBPE CEBPG CKAP4 CREB3 CREBBP CREBZF DAPK3 DDIT3 DISC1 DNMT3L EGLN3 EP300 FOS FOSL1 GABBR2 GCC1 GOLGA1 GOLGA8EP GOLGA8F GPS2 GTF2A1L GTF2B GTF2F2 HAUS7 HK3 JUN JUNB KAT2B LDOC1 LMNB1 MAF MAFB MAP2K7 MDM2 MPZL2 NDC80 NEK6 NFE2 NFE2L1 NFE2L2 NFKBIA NLGN3 POLR2C PTCD3 REPS1 RPS6 SNAP29 SRA1 TBP TGM2 TREX2 TRIB3 TRIM24 TTR ZNF212 ZNF226 10 interacting genes: ATF4 GRN HPGDS IGFBP4 LEP MITF PPP2CB PTGDS STC2 ZBTB17
Entrez ID 468 3101
HPRD ID 06817 00806
Ensembl ID ENSG00000128272 ENSG00000160883
Uniprot IDs P18848 A0A024R7R1 P52790
PDB IDs 1CI6 3HM8
Enriched GO Terms of Interacting Partners?
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