NACA and NUPR1

Number of citations of the paper that reports this interaction (PubMedID 19650074)
16

Data Source:
BioGRID (two hybrid)

		NACA	NUPR1
Description		nascent polypeptide associated complex subunit alpha	nuclear protein 1, transcriptional regulator
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nascent Polypeptide-associated Complex	Nucleus Nucleoplasm Cytoplasm Protein-DNA Complex Perinuclear Region Of Cytoplasm
	Molecular Function	DNA Binding	DNA Binding Chromatin Binding Transcription Coactivator Activity Protein Binding Acetyltransferase Activator Activity
	Biological Process		Acute Inflammatory Response Protein Acetylation Negative Regulation Of Cell Proliferation Male Gonad Development Response To Toxic Substance Regulation Of Autophagy Negative Regulation Of Autophagy Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Positive Regulation Of Protein Modification Process Skeletal Muscle Cell Differentiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Apoptotic Process Positive Regulation Of Catalytic Activity Negative Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Neuron Apoptotic Process Negative Regulation Of Cell Cycle Positive Regulation Of Cell Cycle Negative Regulation Of Glycolytic Process Negative Regulation Of Fibroblast Proliferation Negative Regulation Of Epithelial Cell Proliferation Protein-containing Complex Assembly Positive Regulation Of Neuroinflammatory Response Positive Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Autophagosome Assembly Positive Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Oxidative Phosphorylation Negative Regulation Of Epithelial Cell Apoptotic Process Negative Regulation Of Type B Pancreatic Cell Proliferation Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Female Gonad Development Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Asthma ( 31619474) Atrial fibrillation ( 30061737 29892015) Diastolic blood pressure ( 30224653) QRS duration ( 30012220)	Alcohol consumption (drinks per week) ( 30679032) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 28892062) Crohn's disease ( 28067908) Educational attainment ( 25201988) Extremely high intelligence ( 29520040) Household income (MTAG) ( 31844048) Inflammatory bowel disease ( 28067908 23128233) Inflammatory bowel disease (early onset) ( 19915574) Intelligence (MTAG) ( 29326435) Offspring birth weight ( 31043758) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		16 interacting genes: APLP1 CCDC90B FADD FOS FUNDC2 IGSF21 JUN LRIF1 MDM2 NUPR1 SMYD1 SPP1 TBP TXLNA UCHL5 ZHX1	21 interacting genes: ABCG8 ALDH1A1 EP300 FUS KNSTRN MAPRE1 MPHOSPH6 MSL1 NACA NONO NPY5R PAXIP1 PSMD4 PTMA RAN RANBP1 RPL41 SEC11A SET STX18 SYNCRIP
Entrez ID		4666	26471
HPRD ID		03137	17814
Ensembl ID		ENSG00000196531	ENSG00000176046
Uniprot IDs		A0A024RB41 Q13765	A0A024QZC4 O60356
PDB IDs		3LKX 3MCB 3MCE
Enriched GO Terms of Interacting Partners?
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