MYO7A and USH1C

Number of citations of the paper that reports this interaction (PubMedID 12485990)
153

Data Source:
HPRD (in vivo, in vitro)

		MYO7A	USH1C
Description		myosin VIIA	USH1 protein network component harmonin
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GO Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Cell Cytoplasm Lysosomal Membrane Cytosol Microvillus Cell Cortex Actin Cytoskeleton Apical Plasma Membrane Cell Junction Myosin VII Complex Vesicle Photoreceptor Connecting Cilium Stereocilium Melanosome Synapse Stereocilium Base Upper Tip-link Density	Photoreceptor Outer Segment Photoreceptor Inner Segment Stereocilia Ankle Link Stereocilia Ankle Link Complex Cytoplasm Cytosol Cytoskeleton Plasma Membrane Microvillus Brush Border Photoreceptor Connecting Cilium Stereocilium Stereocilium Tip Apical Part Of Cell Synapse
	Molecular Function	Microfilament Motor Activity Protein Binding Calmodulin Binding ATP Binding Protein Domain Specific Binding Spectrin Binding Actin-dependent ATPase Activity Identical Protein Binding ADP Binding Protein N-terminus Binding Actin Filament Binding	Protein Binding Spectrin Binding Actin Filament Binding
	Biological Process	Phagolysosome Assembly Intracellular Protein Transport Actin Filament Organization Lysosome Organization Sensory Organ Development Visual Perception Sensory Perception Of Sound Actin Filament-based Movement Vesicle Transport Along Actin Filament Cellular Protein Localization Eye Photoreceptor Cell Development Mechanoreceptor Differentiation Post-embryonic Animal Organ Morphogenesis Sensory Perception Of Light Stimulus Equilibrioception Pigment Granule Transport Auditory Receptor Cell Stereocilium Organization	G2/M Transition Of Mitotic Cell Cycle Sensory Perception Of Sound Parallel Actin Filament Bundle Assembly Regulation Of Microvillus Length Cellular Protein-containing Complex Assembly Inner Ear Morphogenesis Inner Ear Auditory Receptor Cell Differentiation Photoreceptor Cell Maintenance Retinal Cone Cell Development Sensory Perception Of Light Stimulus Equilibrioception Actin Filament Bundle Assembly Inner Ear Receptor Cell Development Inner Ear Receptor Cell Stereocilium Organization Protein Localization To Microvillus Brush Border Assembly
Pathways		The canonical retinoid cycle in rods (twilight vision)
Drugs
Diseases		Usher syndrome (US) Deafness, autosomal dominant Deafness, autosomal recessive	Usher syndrome (US) Deafness, autosomal recessive
GWAS		Lewy body disease ( 25188341) Post bronchodilator FEV1/FVC ratio ( 26634245) Tourette syndrome ( 30818990)	Body mass index ( 26426971) Macular thickness ( 30535121) Night sleep phenotypes ( 27126917)
Interacting Genes		12 interacting genes: ACTA1 CALM1 CDH23 KEAP1 KHDRBS1 LINC00839 MAP2 MYRIP PRKAR1A USH1C VEZT WHRN	10 interacting genes: ANKS4B CDH23 CTNNAL1 FBXO7 MIPOL1 MYO7A QKI RAC1 USH1G USHBP1
Entrez ID		4647	10083
HPRD ID		02043	09241
Ensembl ID		ENSG00000137474	ENSG00000006611
Uniprot IDs		Q13402	A0A0S2Z4U9 A0A0S2Z4V1 Q9Y6N9
PDB IDs		5MV9	1X5N 2KBQ 2KBR 2KBS 2LSR 3K1R 5F3X 5MV8 5MV9 5XBF
Enriched GO Terms of Interacting Partners?
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