MYO1D and AATF

		MYO1D	AATF
Description		myosin ID	apoptosis antagonizing transcription factor
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endosome Early Endosome Smooth Endoplasmic Reticulum Cytosol Plasma Membrane Microvillus Brush Border Cell Cortex Actin Cytoskeleton Basolateral Plasma Membrane Myosin Complex Axon Axolemma Cytoplasmic Vesicle Vesicle Neuron Projection Neuronal Cell Body Perikaryon Myelin Sheath Plasma Membrane Raft Extracellular Exosome Apical Dendrite	Nucleus Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Nuclear Transcription Factor Complex
	Molecular Function	Microfilament Motor Activity Calmodulin Binding ATP Binding Protein Domain Specific Binding Actin-dependent ATPase Activity Calcium-dependent Protein Binding Actin Filament Binding	RNA Binding Protein Binding Protein Kinase Binding Leucine Zipper Domain Binding Tau Protein Binding
	Biological Process	Actin Filament Organization Negative Regulation Of Phosphatase Activity Protein Transport Vesicle Transport Along Actin Filament Forebrain Development Cellular Localization Early Endosome To Recycling Endosome Transport	Regulation Of Transcription By RNA Polymerase II Cellular Response To DNA Damage Stimulus Regulation Of Mitotic Cell Cycle Negative Regulation Of Superoxide Anion Generation Ribosome Biogenesis Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Reactive Oxygen Species Metabolic Process Negative Regulation Of Apoptotic Signaling Pathway
Pathways			NRAGE signals death through JNK
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Hypertension risk in short sleep duration ( 22322875) Immature fraction of reticulocytes ( 27863252) Local histogram emphysema pattern ( 25006744) Myopia ( 27182965) Neurofibrillary tangles ( 25188341) Pancreatic cancer ( 20686608) Red cell distribution width ( 27863252) Refractive error ( 23396134) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252) Spherical equivalent or myopia (age of diagnosis) ( 29808027)	Body mass index ( 26426971) Erectile dysfunction ( 30583798) Obesity-related traits ( 23251661)
Interacting Genes		2 interacting genes: AATF PTEN	33 interacting genes: ATM ATR AURKA CCL5 CCL7 CHEK1 CHEK2 CPD DAPK3 DAZAP2 EFNB3 FBXO7 HIPK2 LDOC1 LZTR1 MAPT MPHOSPH6 MPP6 MYO1D NEDD4L NGDN NOS2 NPTN PAWR PCBD2 POLR2J RB1 RELA SMAD3 SP1 SS18L1 TSG101 ZNF468
Entrez ID		4642	26574
HPRD ID		07581	12236
Ensembl ID		ENSG00000176658	ENSG00000275700
Uniprot IDs		J3KRL0 J3QRN6 O94832 Q8N618	Q9NY61
PDB IDs			5W6A
Enriched GO Terms of Interacting Partners?
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