MUSK and COLQ

Number of citations of the paper that reports this interaction (PubMedID 15159418)
40

Data Source:
HPRD (in vivo)

		MUSK	COLQ
Description		muscle associated receptor tyrosine kinase	collagen like tail subunit of asymmetric acetylcholinesterase
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane Cell Junction Neuromuscular Junction Receptor Complex Postsynaptic Membrane	Collagen Trimer Basement Membrane Extracellular Space Plasma Membrane Cell Junction Extracellular Matrix Neuromuscular Junction Synaptic Cleft Collagen-containing Extracellular Matrix
	Molecular Function	Protein Tyrosine Kinase Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Protein Binding ATP Binding Metal Ion Binding	Extracellular Matrix Structural Constituent Protein Binding Heparin Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Multicellular Organism Development Nervous System Development Neuromuscular Junction Development Memory Regulation Of Synaptic Growth At Neuromuscular Junction Positive Regulation Of Gene Expression Positive Regulation Of Neuron Projection Development Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Peptidyl-tyrosine Phosphorylation Positive Regulation Of Kinase Activity Regulation Of MAPK Cascade Positive Regulation Of MAPK Cascade Protein Autophosphorylation Positive Regulation Of ERK1 And ERK2 Cascade Skeletal Muscle Acetylcholine-gated Channel Clustering Positive Regulation Of Protein Geranylgeranylation	Acetylcholine Catabolic Process In Synaptic Cleft Regulation Of Synaptic Growth At Neuromuscular Junction Extracellular Matrix Organization Skeletal Muscle Acetylcholine-gated Channel Clustering Establishment Of Protein Localization To Membrane
Pathways		ECM proteoglycans
Drugs
Diseases		Congenital myasthenic syndrome	Congenital myasthenic syndrome
GWAS		Body mass index ( 28552196) Heel bone mineral density ( 30598549) Metabolite levels ( 23823483) Plasma factor V levels in venous thrombosis (conditioned on rs6027) ( 31271701) Pulmonary function decline ( 22424883) Type 2 diabetes (dietary heme iron intake interaction) ( 23386860)	Diverticular disease ( 30177863 28585551) Diverticulitis ( 28585551)
Interacting Genes		7 interacting genes: COLQ DOK7 ERBIN ILKAP RAPSN STYX SYNE1	4 interacting genes: ACHE BCHE MRPS25 MUSK
Entrez ID		4593	8292
HPRD ID		03190	04328
Ensembl ID		ENSG00000030304	ENSG00000206561
Uniprot IDs		A0A087WSY1 O15146	Q9Y215
PDB IDs			1VZJ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?