MMP10 and HAPLN1

Number of citations of the paper that reports this interaction (PubMedID 7694569)
17

Data Source:
HPRD (in vitro)

		MMP10	HAPLN1
Description		matrix metallopeptidase 10	hyaluronan and proteoglycan link protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Matrix	Extracellular Region Extracellular Matrix Synapse Collagen-containing Extracellular Matrix
	Molecular Function	Metalloendopeptidase Activity Zinc Ion Binding	Hyaluronic Acid Binding Extracellular Matrix Structural Constituent Conferring Compression Resistance
	Biological Process	Proteolysis Extracellular Matrix Disassembly Extracellular Matrix Organization Collagen Catabolic Process	Skeletal System Development Cell Adhesion Central Nervous System Development Extracellular Matrix Organization
Pathways		Collagen degradation Collagen degradation Degradation of the extracellular matrix Degradation of the extracellular matrix Activation of Matrix Metalloproteinases	ECM proteoglycans
Drugs		Marimastat N-ISOBUTYL-N-[4-METHOXYPHENYLSULFONYL]GLYCYL HYDROXAMIC ACID	Hyaluronic acid
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Multiple sclerosis ( 23412934) Prostate cancer ( 23535732)	Ankylosing spondylitis ( 22138694) Blood protein levels ( 30072576) Diisocyanate-induced asthma ( 25918132) Gastroesophageal reflux disease ( 31527586) Metabolite levels ( 23823483) Prostate cancer ( 17903305) Visceral fat ( 22589738) Waist circumference ( 28552196) White matter integrity (fractional anisotropy) ( 29752348) White matter integrity (mean diffusivity) ( 29752348)
Interacting Genes		3 interacting genes: BCAN HAPLN1 MMP9	8 interacting genes: ACAN APP MMP10 MMP2 MMP3 MMP7 MMP9 VCAN
Entrez ID		4319	1404
HPRD ID		01704	00275
Ensembl ID		ENSG00000166670	ENSG00000145681
Uniprot IDs		P09238	A0A024RAK9 P10915
PDB IDs		1Q3A 3V96 4ILW
Enriched GO Terms of Interacting Partners?
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