MMP8 and UMOD

  • Number of citations of the paper that reports this interaction (PubMedID 8397318)
  • 10
  • Data Source:
  • HPRD (in vitro)

MMP8

UMOD

Description matrix metallopeptidase 8 uromodulin
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Chronic kidney disease ( 29124443 26831199 20383146)
  • Chronic kidney disease and serum creatinine levels ( 20686651)
  • Creatinine levels ( 29124443)
  • Diastolic blood pressure ( 27841878)
  • Diastolic blood pressure x smoking status (ever vs never) interaction (1df test) ( 29455858)
  • Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
  • Estimated glomerular filtration rate ( 31015462 29124443 30604766)
  • Femoral neck bone geometry ( 22087292)
  • Glomerular filtration rate ( 27588450)
  • Glomerular filtration rate (creatinine) ( 28452372 26831199)
  • Glomerular filtration rate (cystatin C) ( 28452372)
  • Glomerular filtration rate in diabetes ( 29703844)
  • Glomerular filtration rate in diabetics (creatinine) ( 26831199)
  • Glomerular filtration rate in non diabetics (creatinine) ( 26831199)
  • Glomerular filtration rate in type 2 diabetes ( 29703844)
  • Hypertension ( 27618447 21082022)
  • Hyperuricemia ( 29124443)
  • Kidney function decline traits ( 25493955)
  • Kidney stones ( 31729369)
  • Medication use (calcium channel blockers) ( 31015401)
  • Renal function and chronic kidney disease ( 19430482)
  • Renal function-related traits (eGRFcrea) ( 22797727)
  • Renal function-related traits (sCR) ( 22797727)
  • Serum uric acid levels ( 29124443)
  • Urate levels ( 31578528)
  • Urinary uromodulin levels ( 24578125)
Interacting Genes 7 interacting genes: ACAN BCAN CCL2 FBXO7 TFPI TIMP2 UMOD 2 interacting genes: LTA MMP8
Entrez ID 4317 7369
HPRD ID 00385 11771
Ensembl ID ENSG00000118113 ENSG00000169344
Uniprot IDs B4E0I2 P22894 P07911
PDB IDs 1A85 1A86 1BZS 1I73 1I76 1JAN 1JAO 1JAP 1JAQ 1JH1 1JJ9 1KBC 1MMB 1MNC 1ZP5 1ZS0 1ZVX 2OY2 2OY4 3DNG 3DPE 3DPF 3TT4 4QKZ 5H8X 4WRN
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
Tagcloud (Intersection) ?