DDI1 and KLHL42

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

		DDI1	KLHL42
Description		DNA damage inducible 1 homolog 1	kelch like family member 42
Image			No pdb structure
GO Annotations	Cellular Component		Spindle Cytosol Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Aspartic-type Endopeptidase Activity Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding
	Biological Process	Proteasomal Protein Catabolic Process Regulation Of Protein Stability Cellular Response To Hydroxyurea Regulation Of DNA Stability	Protein Polyubiquitination Cell Cycle Regulation Of Microtubule-based Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification Cell Division
Pathways			Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	Gut microbiota (functional units) ( 27694959) Height ( 31562340) Osteoarthritis (hip) ( 30664745) Resting heart rate ( 27798624) Type 2 diabetes ( 30054458)
Interacting Genes		8 interacting genes: ADRM1 CCL28 CYGB DVL2 KLHL42 MFHAS1 UBC UBE2K	15 interacting genes: CALCOCO2 COIL CUL3 DDI1 FAM168A RCN3 SERTAD1 SSX2IP STAM2 STXBP4 TRIM23 UBE2E3 UBQLN1 UBQLN4 USHBP1
Entrez ID		414301	57542
HPRD ID		13128	17237
Ensembl ID		ENSG00000170967	ENSG00000087448
Uniprot IDs		Q8WTU0	B2RNT7 F5H523 Q9P2K6
PDB IDs		3S8I
Enriched GO Terms of Interacting Partners?
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