MAP1A and ARHGEF11

Number of citations of the paper that reports this interaction (PubMedID 16478718)
10

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		MAP1A	ARHGEF11
Description		microtubule associated protein 1A	Rho guanine nucleotide exchange factor 11
Image		No pdb structure
GO Annotations	Cellular Component	Cell Cytoplasm Cytosol Microtubule Microtubule Associated Complex Axon Dendrite Cell Projection Neuron Projection Neuronal Cell Body Axon Initial Segment Dendritic Shaft Dendritic Branch Synapse Primary Dendrite Dendritic Microtubule Axon Cytoplasm	Cytoplasm Cytosol Membrane
	Molecular Function	Actin Binding Structural Molecule Activity Protein Binding Microtubule Binding Cytoskeletal Adaptor Activity Tubulin Binding Tau Protein Binding	G Protein-coupled Receptor Binding Rho Guanyl-nucleotide Exchange Factor Activity GTPase Activator Activity Protein Binding
	Biological Process	Microtubule Cytoskeleton Organization Axonogenesis Memory Associative Learning Dendrite Development Regulation Of Microtubule Depolymerization Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Synaptic Plasticity Voluntary Musculoskeletal Movement Neuron Cellular Homeostasis Anterograde Axonal Protein Transport Retrograde Axonal Protein Transport Negative Regulation Of Protein Localization To Microtubule Positive Regulation Of Cellular Protein Localization Neuron Projection Maintenance Positive Regulation Of Protein Localization To Cell Surface	Regulation Of Cell Growth Striated Muscle Contraction G Protein-coupled Receptor Signaling Pathway Rho Protein Signal Transduction Establishment Of Cell Polarity Actin Cytoskeleton Organization Positive Regulation Of Apoptotic Process Positive Regulation Of GTPase Activity Positive Regulation Of Transcription, DNA-templated Regulation Of Small GTPase Mediated Signal Transduction
Pathways			NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events Sema4D induced cell migration and growth-cone collapse
Drugs		Estramustine
Diseases
GWAS		Platelet count ( 27863252) Plateletcrit ( 27863252) Triglycerides ( 24507774 30275531)	Chin dimples ( 27182965) Heel bone mineral density ( 30598549) Height ( 31562340)
Interacting Genes		23 interacting genes: ACTA1 ACTG1 AP1G1 ARHGEF11 CACNB4 DISC1 DLG1 DLG2 DLG4 GRB2 HTR2A KCNMA1 MAP1B MAP1LC3A NXF1 NXF2 RAPGEF3 RAPGEF4 RHOB SPP1 TUBA4A TUBB UPF2	15 interacting genes: ABCA1 CDC42 GNA12 GNA13 LPAR1 LPAR2 MAP1A MAP1B PLXNB1 PLXNB2 PLXNB3 PTPRF RHOA RPS6KA1 SLC1A6
Entrez ID		4130	9826
HPRD ID		02549	09302
Ensembl ID		ENSG00000166963	ENSG00000132694
Uniprot IDs		P78559 Q504X9	O15085
PDB IDs			1HTJ 1XCG 2DLS 3KZ1 3T06 5E6P 5JHG 5JHH 5TYT
Enriched GO Terms of Interacting Partners?
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