SMAD5 and SMURF2

  • Number of citations of the paper that reports this interaction (PubMedID 15231748)
  • 85
  • Data Source:
  • HPRD (two hybrid)

SMAD5

SMURF2

Description SMAD family member 5 SMAD specific E3 ubiquitin protein ligase 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Insomnia symptoms (never/rarely vs. sometimes/usually) ( 30804566)
  • Insomnia symptoms (never/rarely vs. usually) ( 30804566)
  • Sleep duration (short sleep) ( 30846698)
Interacting Genes 44 interacting genes: ACVR1 ANKRD13A BCAT1 BMP6 CHMP3 COPS5 CXXC5 EP300 FLNA GDF6 HBG2 HGS HOXA13 HOXD13 MBD1 MEN1 MTMR10 NEDD4 PLEKHO1 PNKP PPIL4 PSMD11 PTPN12 RBM4 RYR2 SF3B1 SF3B3 SFPQ SMAD1 SMAD4 SMURF1 SMURF2 SNRNP70 SNRPA SOX5 SOX7 SUV39H1 SUV39H2 TOB1 U2AF2 UBA1 WWP1 ZEB2 ZNF8 90 interacting genes: ABRAXAS2 ACBD3 ACOX3 AIMP2 ANAPC5 ARHGAP5 ASH2L AXIN1 BTRC CANX CNKSR2 CUEDC1 DAB2 DAZAP2 DGCR2 EGFR EPHA1 FKBP4 FLNB FUBP1 GNG2 HDGFL3 ING2 IRF3 IRF8 ITGB1BP1 KLF5 LAPTM5 LATS1 LMNA MAVS NEK6 NKIRAS1 NRAS PDE4B PPID PRICKLE1 PRICKLE2 RAB13 RAB14 RAB17 RAB22A RAB25 RAN RAP1B RASD2 RASL12 RHOA RHOD RLIM RNF11 RNF111 RNF2 RNF20 RPS27A RRAS2 RUNX2 RUNX3 SF3A2 SKIL SMAD1 SMAD2 SMAD3 SMAD5 SMAD6 SMAD7 SMAP1 SNCA SNRNP70 SOCS6 SPART SRSF4 TFPI2 TGFBR1 TMEM139 TNPO3 TOP2A TRAF2 TRAF4 TSSK4 TXNIP UBC UBE2D1 UBE2D2 UBE2D3 UBE2L3 USP15 XPO1 YY1 ZBTB44
Entrez ID 4090 64750
HPRD ID 04381 06901
Ensembl ID ENSG00000113658 ENSG00000108854
Uniprot IDs Q68DB7 Q99717 Q96DE7 Q9HAU4
PDB IDs 6FZS 6TCE 1ZVD 2DJY 2JQZ 2KXQ 2LTZ 6FX4
Enriched GO Terms of Interacting Partners?
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