LRP6 and DKK1

  • Number of citations of the paper that reports this interaction (PubMedID 11357136)
  • 326
  • Data Source:
  • HPRD (in vivo)

LRP6

DKK1

Description LDL receptor related protein 6 dickkopf WNT signaling pathway inhibitor 1
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Cerebrospinal fluid t-tau levels in normal cognition ( 29274321)
  • Cerebrospinal fluid t-tau:AB1-42 ratio ( 28641921)
  • Coronary artery calcification ( 23870195)
  • Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
  • Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
  • Heel bone mineral density ( 30598549)
  • Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
  • Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
  • Tandem gait ( 26219847)
Interacting Genes 16 interacting genes: ANTXR1 ANTXR2 APOB ATP13A2 AXIN1 DKK1 DKK2 FZD5 FZD8 GSK3B LRRK2 MDK SERPINF1 TLNRD1 WNT1 WNT3A 8 interacting genes: CKAP4 DPP4 KREMEN1 KRTAP10-1 LRP5 LRP6 MDFI SMAD9
Entrez ID 4040 22943
HPRD ID 04617 05544
Ensembl ID ENSG00000070018 ENSG00000107984
Uniprot IDs O75581 I1W660 O94907
PDB IDs 3S2K 3S8V 3S8Z 3S94 3SOB 3SOQ 3SOV 4A0P 4DG6 4NM5 4NM7 5AIR 5FWW 5GJE 6H15 6H16 3S2K 3S8V 3SOQ 5FWW 5GJE
Enriched GO Terms of Interacting Partners?
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