ARL2 and TBCD

Number of citations of the paper that reports this interaction (PubMedID 10831612)
69

Data Source:
HPRD (in vitro, in vivo)

		ARL2	TBCD
Description		ADP ribosylation factor like GTPase 2	tubulin folding cofactor D
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Mitochondrial Intermembrane Space Mitochondrial Matrix Golgi Apparatus Centrosome Cytosol Focal Adhesion Cilium Microtubule Cytoskeleton Lateral Plasma Membrane	Cytoplasm Centrosome Microtubule Bicellular Tight Junction Lateral Plasma Membrane
	Molecular Function	GTPase Activity GTPase Inhibitor Activity Protein Binding GTP Binding GDP Binding	GTPase Activator Activity Protein Binding Beta-tubulin Binding Chaperone Binding
	Biological Process	Tubulin Complex Assembly Centrosome Cycle Positive Regulation Of Cell-substrate Adhesion Regulation Of Microtubule Polymerization Positive Regulation Of Microtubule Polymerization Negative Regulation Of GTPase Activity Regulation Of Insulin Secretion Maintenance Of Protein Location In Nucleus Bicellular Tight Junction Assembly	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Protein Folding Tubulin Complex Assembly Post-chaperonin Tubulin Folding Pathway Negative Regulation Of Cell-substrate Adhesion Negative Regulation Of Microtubule Polymerization Adherens Junction Assembly Positive Regulation Of GTPase Activity Cell Morphogenesis Involved In Neuron Differentiation Bicellular Tight Junction Assembly
Pathways		Post-chaperonin tubulin folding pathway Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane	Post-chaperonin tubulin folding pathway
Drugs
Diseases
GWAS			Blond vs. brown/black hair color ( 30531825) Bone mineral accretion in asthma (oral corticosteroid dose interaction) ( 26025128) Moderate-to-late spontaneous preterm birth ( 31194736) Response to cognitive-behavioural therapy in anxiety and major depressive disorders ( 31123309)
Interacting Genes		6 interacting genes: ARL2BP PDE6D POLA2 TBCD TBL1XR1 UNC119	13 interacting genes: ACD APP ARL2 DEXI MTDH MTNR1B POLR2I POT1 SMAD9 TBCE TERF1 TUBB XRCC6
Entrez ID		402	6904
HPRD ID		11869	05227
Ensembl ID		ENSG00000213465	ENSG00000141556
Uniprot IDs		P36404 Q53YD8	Q9BTW9
PDB IDs		3DOE 3DOF
Enriched GO Terms of Interacting Partners?
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