CENPP and KLC3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CENPP	KLC3
Description		centromere protein P	kinesin light chain 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Nucleus Nucleoplasm Nucleolus Cytosol	Cytoplasm Kinesin Complex Microtubule Motile Cilium Ciliary Rootlet Neuron Projection
	Molecular Function	Protein Binding	Microtubule Motor Activity Protein Binding Microtubule Binding Kinesin Binding
	Biological Process	CENP-A Containing Nucleosome Assembly	Axo-dendritic Transport
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS		Blood protein levels ( 29875488) End-stage renal disease ( 29885931) Height ( 28552196 31562340) Pulse pressure ( 30578418) Systolic blood pressure ( 30224653 30578418) Urate levels ( 31578528)	Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971)
Interacting Genes		9 interacting genes: CCDC33 GOLGA2 KLC3 LMNA NHLH1 RPIA TEX11 USHBP1 ZNF341	37 interacting genes: ABI3 BBS5 BICDL2 CBY2 CCNH CENPP CEP57L1 CROCC DTX2 GEM IHO1 IMP3 KDM1A KIF5A KIF5B KIF5C KRT13 KRT15 MBIP NDC80 NECAB2 NEFL PDE4DIP QARS1 SMARCB1 SNAP47 STX11 TCF4 TSNAX USHBP1 VPS52 WAC YWHAG YWHAH YWHAQ ZNF417 ZNF572
Entrez ID		401541	147700
HPRD ID		17989	03212
Ensembl ID		ENSG00000188312	ENSG00000104892
Uniprot IDs		Q6IPU0 Q7Z672	A0A024R0V3 Q6P597
PDB IDs
Enriched GO Terms of Interacting Partners?
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