LOX and ZNF202

		LOX	ZNF202
Description		lysyl oxidase	zinc finger protein 202
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Extracellular Space Cell Nucleus Extracellular Matrix	Nucleolus Nuclear Body
	Molecular Function	Protein-lysine 6-oxidase Activity Copper Ion Binding Protein Binding Collagen Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding
	Biological Process	Osteoblast Differentiation Regulation Of Protein Phosphorylation Cellular Protein Modification Process Heart Development Regulation Of Gene Expression Regulation Of Striated Muscle Tissue Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Peptidyl-lysine Oxidation Extracellular Matrix Organization Collagen Fibril Organization Bone Mineralization Lung Development Platelet-derived Growth Factor Receptor-beta Signaling Pathway Ascending Aorta Development Descending Aorta Development Wound Healing Response To Drug Regulation Of Apoptotic Process Protein Kinase B Signaling Regulation Of Megakaryocyte Differentiation Muscle Cell Cellular Homeostasis Elastic Fiber Assembly Blood Vessel Morphogenesis Response To Steroid Hormone Muscle Fiber Development Cell Chemotaxis Connective Tissue Development DNA Biosynthetic Process Regulation Of Receptor Binding Regulation Of Bone Development Cellular Response To Chemokine Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway	Negative Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Lipid Metabolic Process
Pathways		Elastic fibre formation Crosslinking of collagen fibrils	Generic Transcription Pathway
Drugs
Diseases
GWAS		Coronary artery disease ( 28714974) Intraocular pressure ( 29617998) Lung function (FEV1/FVC) ( 30804560) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)	Response to antipsychotic therapy (extrapyramidal side effects) ( 19875103) Response to citalopram or escitalopram in depression ( 27622933)
Interacting Genes		15 interacting genes: DHDDS DPT ELN EYA2 GAP43 H1-1 H1-5 H2BC11 H2BC21 MYL4 NAMPT RAF1 SNX24 ZNF202 ZNF608	8 interacting genes: KRT40 KRTAP10-3 LOX MZF1 PCBD1 SCAND1 SNX2 ZNF473
Entrez ID		4015	7753
HPRD ID		01087	04577
Ensembl ID		ENSG00000113083	ENSG00000166261
Uniprot IDs		B0AZT2 B7ZAJ4 D0PNI2 P28300	A0A024R3M3 B3KN61 O95125
PDB IDs
Enriched GO Terms of Interacting Partners?
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