LMO2 and ZFP64

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		LMO2	ZFP64
Description		LIM domain only 2	ZFP64 zinc finger protein
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GO Annotations	Cellular Component	Nucleoplasm Transcription Factor Complex	Nucleus
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Activating Transcription Factor Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding BHLH Transcription Factor Binding Metal Ion Binding Cofactor Binding E-box Binding	DNA Binding Protein Binding Metal Ion Binding
	Biological Process	Multicellular Organism Development MRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Thyroid Hormone Stimulus Regulation Of Hematopoietic Stem Cell Differentiation
Pathways		RUNX1 regulates transcription of genes involved in differentiation of HSCs
Drugs
Diseases		Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
GWAS		Cognitive performance ( 19734545) Iron status biomarkers (transferrin saturation) ( 28334935) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Red blood cell count ( 27863252)	Amyotrophic lateral sclerosis ( 17362836) BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 28892062 25673413) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Hand grip strength ( 29691431) Parkinson's disease ( 26227905) Reading disability or specific language impairment (pleiotropy) ( 25065397) Subcutaneous adipose tissue ( 22589738) Urinary metabolite levels in chronic kidney disease ( 29545352) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683) Waist circumference ( 25673412) Waist-hip ratio ( 25673412)
Interacting Genes		97 interacting genes: ABI2 ADAMTSL4 AFDN AGTRAP AIMP2 ALDH6A1 AXIN1 BANP BEX2 BLZF1 C1orf94 CALCOCO2 CBY2 CCDC33 CDC25A CDC5L CDX4 CLHC1 CMTM5 CORO1A CORO1C DAZAP2 DBF4B DDIT3 DRAP1 EHMT2 ELF2 ERBIN FHL3 GATA1 GATA2 GATA3 GFAP GOLGA2 GRB2 HNRNPC HNRNPM HOOK1 IFT43 IHO1 IKZF3 ISL1 KANK2 KDM5A KIF3B KRT15 KRT40 KRTAP10-7 LDB1 LYL1 LZTS2 MAGEA8 MAPRE1 MAPRE2 MAPRE3 MBIP MRFAP1L1 MTUS2 N4BP2L2 NCAPH2 NHLH1 NIF3L1 NOTCH2NLA NUP62 NUTM1 PDE9A PHC2 PRKG1 RBBP8 REL RELA RINT1 RLIM ROCK1 SAXO1 SKP1 SMAD2 SOX5 SP1 SSX2IP STAT1 STAT3 STIP1 TAL1 TAL2 TFPT TLE5 TLX3 TRIM23 TRIM54 TRIP6 TSC22D4 TUFT1 UBA6 UBE2I ZFP64 ZNF24	26 interacting genes: AEN BARD1 BEGAIN BYSL EMD ERG28 FAM124A FHL2 L3MBTL2 LMO2 LNX1 MAFB MFAP1 MTUS2 PBK PPARGC1B PRPF31 RBM10 RHOU SETDB1 TLE1 TRIM41 UNC119 ZBTB9 ZNF513 ZNF70
Entrez ID		4005	55734
HPRD ID		01586	15728
Ensembl ID		ENSG00000135363	ENSG00000020256
Uniprot IDs		P25791	B3KQX0 Q9NTW7
PDB IDs		2XJY 2XJZ 2YPA 4KFZ	1X5W 2DMD
Enriched GO Terms of Interacting Partners?
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