ARL1 and GCC1

Number of citations of the paper that reports this interaction (PubMedID 12972563)
47

Data Source:
BioGRID (two hybrid)

		ARL1	GCC1
Description		ADP ribosylation factor like GTPase 1	GRIP and coiled-coil domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Trans-Golgi Network Cytosol Trans-Golgi Network Membrane	Golgi Membrane Golgi Apparatus Cytosol
	Molecular Function	GTPase Activity GTP Binding Enzyme Activator Activity Protein Domain Specific Binding Metal Ion Binding	Protein Binding
	Biological Process	Intracellular Protein Transport Golgi Organization Toxin Metabolic Process Vesicle-mediated Transport Activation Of Phospholipase D Activity Protein Localization To Golgi Apparatus Retrograde Transport, Endosome To Golgi Golgi Vesicle Transport
Pathways		Retrograde transport at the Trans-Golgi-Network	Retrograde transport at the Trans-Golgi-Network
Drugs		Guanosine-5'-Diphosphate
Diseases
GWAS		Lung cancer in never smokers ( 28604730) Response to methotrexate in juvenile idiopathic arthritis ( 24709693)	Feeling worry ( 29500382) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Medication adherence in chronic diseases ( 25317111) Type 2 diabetes ( 26818947 22158537 30718926)
Interacting Genes		7 interacting genes: ARFIP2 COPG2 GCC1 GCC2 GOLGA1 GOLGA4 SCOC	44 interacting genes: ABI2 ADGRE5 AMOTL2 APP ARL1 ATF4 ATN1 BIRC2 BRCA1 C1orf94 CCDC85B CEP57 CEP70 COIL CPSF7 CRHR2 DNAJA3 FAM71F2 FBF1 GLI1 GOLGA2 GTF2I HILPDA IKBKG ITSN1 KHSRP KIAA0753 KIAA1217 LZTS2 MCRS1 NAB2 NAV1 NECAB2 NINL OIP5 PAK5 PCDHA1 RBM28 SMARCD1 SPOP TFIP11 TRIM29 USHBP1 ZNF276
Entrez ID		400	79571
HPRD ID		04574	07599
Ensembl ID		ENSG00000120805	ENSG00000179562
Uniprot IDs		B4DZG7 P40616	A4D0Z4 Q96CN9
PDB IDs		1UPT 4DCN 5EE5 5J5C
Enriched GO Terms of Interacting Partners?
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