TBPL2 and KPNA2

Number of citations of the paper that reports this interaction (PubMedID 15234975)
30

Data Source:
BioGRID (pull down, pull down)

		TBPL2	KPNA2
Description		TATA-box binding protein like 2	karyopherin subunit alpha 2
Image		No pdb structure
GO Annotations	Cellular Component	Transcription Factor TFIIIB Complex Nucleus Transcription Factor Complex Transcription Factor TFIID Complex Cytoplasm	Nuclear Pore Nucleoplasm Cytoplasm Cytosol Membrane Host Cell Extrinsic Component Of Postsynaptic Specialization Membrane Glutamatergic Synapse
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding RNA Polymerase II Core Promoter Sequence-specific DNA Binding RNA Polymerase III Regulatory Region DNA Binding DNA-binding Transcription Factor Activity Transcription Factor Binding	RNA Binding Protein Binding Nuclear Localization Sequence Binding Histone Deacetylase Binding Nuclear Import Signal Receptor Activity
	Biological Process	Transcription By RNA Polymerase II Multicellular Organism Development Negative Regulation Of Transcription, DNA-templated RNA Polymerase III Preinitiation Complex Assembly	Regulation Of DNA Recombination DNA Metabolic Process NLS-bearing Protein Import Into Nucleus Modulation By Virus Of Host Process Entry Of Viral Genome Into Host Nucleus Through Nuclear Pore Complex Via Importin Postsynapse To Nucleus Signaling Pathway Positive Regulation Of Viral Life Cycle
Pathways			CaMK IV-mediated phosphorylation of CREB ISG15 antiviral mechanism NS1 Mediated Effects on Host Pathways CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde Sensing of DNA Double Strand Breaks Estrogen-dependent gene expression
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Early spontaneous preterm birth ( 31194736) Pediatric bone mineral content (femoral neck) ( 28181694) Pediatric bone mineral density (femoral neck) ( 28181694) Pediatric bone mineral density (hip) ( 28181694) Platelet count ( 27863252) Testicular germ cell tumor ( 28604728)	Feeling lonely ( 29500382) General risk tolerance (MTAG) ( 30643258) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Regular attendance at a religious group ( 29970889)
Interacting Genes		4 interacting genes: DNAJB4 DNAJB5 KPNA2 MAP4K4	105 interacting genes: ACTN1 ACTN4 ANKIB1 AP2B1 APOBEC1 APP ARL4A ARL5A BAG6 BRCA1 BTBD2 CASP2 CCDC107 CDA CDK5RAP3 CHD3 CHEK2 CORO1B CREB3L3 CREBBP CSE1L CSNK1A1 CUL4B DCTN2 DDIT3 EP300 EPB41 FEZ2 FN1 FTH1 GART GMCL1 GRB2 GTF2IRD1 H1-0 HAP1 HMG20A HNRNPC HOMER2 HOMEZ HSPA4 IFT20 IMMT INO80E ITK JUN KLC4 KPNB1 KRT18 KRT40 KRT8 LAMB2 LEF1 LZTS2 MAGED1 MAGEH1 MDFI MLH1 MORC3 MVP NECAB2 NFKBIB NMNAT1 NR3C1 NUP153 NUP50 NUP62 NUTM1 PAX5 PLAG1 PNMA5 PRKD3 PTMA RAG1 RAN RANBP2 RBM48 RBPMS RECQL RELA RELB RGL2 RILP RNMT SART3 SERTAD3 SGK1 SLC2A2 SPRY1 SRPK1 TADA2A TAF3 TAF8 TANK TBPL2 TP53 TRAF1 TRIM54 TSC22D4 TXNIP UBR5 USHBP1 ZBTB7B ZC3H12A ZNF131
Entrez ID		387332	3838
HPRD ID		10607	02818
Ensembl ID		ENSG00000182521	ENSG00000182481
Uniprot IDs		Q6SJ96	P52292
PDB IDs			1EFX 1QGK 1QGR 3FEX 3FEY 3WPT 4E4V 4WV6 5H43
Enriched GO Terms of Interacting Partners?
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