KRTAP10-7 and WNT11

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		KRTAP10-7	WNT11
Description		keratin associated protein 10-7	Wnt family member 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Keratin Filament	Extracellular Region Extracellular Space Cytoplasm Extracellular Matrix
	Molecular Function	Protein Binding Identical Protein Binding	GTPase Activator Activity Frizzled Binding Protein Binding Protein Kinase Activator Activity Transcription Regulatory Region DNA Binding
	Biological Process	Keratinization	Osteoblast Differentiation Epithelial To Mesenchymal Transition Primary Heart Field Specification Secondary Heart Field Specification Outflow Tract Morphogenesis Atrial Septum Development Planar Cell Polarity Pathway Involved In Axis Elongation Protein Phosphorylation Wnt Signaling Pathway, Calcium Modulating Pathway Positive Regulation Of Gene Expression Wnt Signaling Pathway Neuron Differentiation Bone Mineralization Negative Regulation Of Cell Growth Adrenal Gland Development Positive Regulation Of Cell Migration Negative Regulation Of Cell Migration Response To Nutrient Levels Activation Of Protein Kinase Activity Positive Regulation Of Transforming Growth Factor Beta2 Production Protein Localization To Cell Surface Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of GTPase Activity Cell Fate Commitment Maintenance Of Epithelial Cell Apical/basal Polarity Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Paraxial Mesoderm Formation Notochord Morphogenesis Embryonic Skeletal System Development Artery Morphogenesis Positive Regulation Of Stress Fiber Assembly Convergent Extension Involved In Axis Elongation Canonical Wnt Signaling Pathway Wnt Signaling Pathway, Planar Cell Polarity Pathway Cloacal Septation Ventricular Septum Morphogenesis Lung-associated Mesenchyme Development Negative Regulation Of Cell Death Ureteric Bud Morphogenesis Planar Cell Polarity Pathway Involved In Gastrula Mediolateral Intercalation Negative Regulation Of Cartilage Development Somite Development Neuroendocrine Cell Differentiation Secondary Palate Development Bicellular Tight Junction Assembly Cellular Response To Mechanical Stimulus Cellular Response To Retinoic Acid Mesonephric Duct Development Negative Regulation Of Mesenchymal Cell Proliferation Positive Regulation Of Protein Kinase C Signaling Positive Regulation Of Heart Induction By Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Fibroblast Growth Factor Production
Pathways		Keratinization	WNT ligand biogenesis and trafficking WNT ligand biogenesis and trafficking Class B/2 (Secretin family receptors) Ca2+ pathway Ca2+ pathway PCP/CE pathway PCP/CE pathway
Drugs
Diseases
GWAS			Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 30929738 31619474) Asthma (adult onset) ( 30929738) Asthma (childhood onset) ( 30929738) Asthma onset (childhood vs adult) ( 30929738) PR interval ( 30046033 20062060)
Interacting Genes		217 interacting genes: AEN ALDH3B1 ANKRD36BP1 AP1M1 APP AQP1 AVPI1 B4GALT7 BAHD1 BCL6B BMP7 BUD31 BYSL C19orf57 C8orf33 CARHSP1 CATIP CBX2 CCDC185 CCDC26 CCNG1 CDCA7L CHIC2 CHRD CHRNG CLK1 CLK4 COL8A1 CRCT1 CREB5 CSNK1G1 CSNK1G2 CTNNBIP1 CTRC CXCL16 DAAM2 DERL2 DHX57 DMRT3 E2F6 E4F1 EHHADH FAM124B FAM161A FAM27E3 FAM74A4 FAM76B FARS2 GABARAPL1 GABARAPL2 GEM GLIDR GLP1R GNE GOLGA8EP GRN GSTP1 GUCD1 HBZ HHEX HPCAL1 HSBP1 HSD3B7 IGSF8 ING5 INPP5D IQUB KLHL38 KRT20 KRT83 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP4-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 LCE1B LCE2A LCE3E LCE4A LIMS2 LINC00242 LMNA LMO2 LRCH4 MAPKBP1 MCM5 MOBP MRGBP MXD3 MXI1 NAA10 NAXD NECTIN2 NECTIN3 NOL12 NOTCH2NLA NPBWR2 NPDC1 NTAQ1 NUBP2 NUDCD3 NUFIP2 P2RY6 PCED1A PCSK5 PDIA5 PDLIM5 PFKL PGAP6 PIN1 POLL POM121L8P PPARD PRKAB2 PRM2 PRR13 PTGDS PTGER3 PTPMT1 PVR RNF175 RPF1 RPL11 RPL36AL RPS28 RPUSD3 RSPO2 RTN4RL1 RWDD2B SCNM1 SDCBP SHFL SLC23A1 SLC25A48 SLC6A20 SMCO4 SMCP SPACA9 SPATA3 SPATA8 SPG7 SPRY1 SSX2IP STAT3 STK16 SUV39H1 TAPBPL TCEA2 TCEANC TEDC2 THAP1 THAP6 TLE5 TMA16 TNP2 TNS2 TOR1A TREX1 TRIM42 TULP3 TXNDC5 TYRO3 UCP2 UXT VTI1B WNT11 WT1 ZBTB24 ZBTB38 ZBTB9 ZFYVE26 ZNF101 ZNF124 ZNF133 ZNF155 ZNF165 ZNF169 ZNF175 ZNF180 ZNF2 ZNF20 ZNF223 ZNF250 ZNF26 ZNF266 ZNF32 ZNF320 ZNF329 ZNF337 ZNF41 ZNF417 ZNF418 ZNF419 ZNF425 ZNF433 ZNF439 ZNF490 ZNF543 ZNF555 ZNF564 ZNF572 ZNF578 ZNF581 ZNF587 ZNF625 ZNF670 ZNF697 ZNF707 ZNF778 ZNF792 ZNF846 ZNHIT1 ZSCAN26	3 interacting genes: KRTAP10-7 KRTAP10-9 MDFI
Entrez ID		386675	7481
HPRD ID		11193	04741
Ensembl ID		ENSG00000272804	ENSG00000085741
Uniprot IDs		P60409	O96014
PDB IDs
Enriched GO Terms of Interacting Partners?
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