TNPO1 and NUP98

Number of citations of the paper that reports this interaction (PubMedID 26344197)
117

Data Source:
BioGRID (biochemical)
HPRD (in vitro)

		TNPO1	NUP98
Description		transportin 1	nucleoporin 98 and 96 precursor
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Cilium Extracellular Exosome	Kinetochore Nuclear Envelope Nuclear Pore Nucleoplasm Cytosol Nuclear Body Nuclear Pore Outer Ring Nuclear Membrane Nuclear Periphery Nuclear Inclusion Body Intracellular Membrane-bounded Organelle Host Cell Nuclear Pore Cytoplasmic Filaments Nuclear Pore Nuclear Basket Ribonucleoprotein Complex
	Molecular Function	RNA Binding Protein Binding Nuclear Localization Sequence Binding Ran GTPase Binding Nuclear Import Signal Receptor Activity	Transcription Coactivator Activity RNA Binding MRNA Binding Transporter Activity Protein Binding Nuclear Localization Sequence Binding Serine-type Peptidase Activity Structural Constituent Of Nuclear Pore Promoter-specific Chromatin Binding
	Biological Process	Protein Import Into Nucleus Viral Process Intraciliary Transport Involved In Cilium Assembly Regulation Of MRNA Stability	Posttranscriptional Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Regulation Of Glycolytic Process RNA Export From Nucleus MRNA Export From Nucleus TRNA Export From Nucleus Proteolysis Protein Import Into Nucleus Nucleocytoplasmic Transport Nuclear Pore Organization Viral Process Protein Sumoylation Viral Transcription Telomere Tethering At Nuclear Periphery Positive Regulation Of MRNA Splicing, Via Spliceosome Nuclear Pore Complex Assembly Regulation Of Gene Silencing By MiRNA Intracellular Transport Of Virus Regulation Of Cellular Response To Heat Positive Regulation Of Nucleic Acid-templated Transcription
Pathways		Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA Intraflagellar transport Postmitotic nuclear pore complex (NPC) reformation
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease ( 30804561) Factor VIII levels ( 30586737) Height ( 31562340) Mean corpuscular hemoglobin concentration ( 29403010 27863252) Mean platelet volume ( 27863252) Medication use (thyroid preparations) ( 31015401) Platelet count ( 27863252) Red cell distribution width ( 28957414) Serum albumin level ( 29403010) vWF levels ( 30586737)	Metabolite levels (Dihydroxy docosatrienoic acid) ( 23934736)
Interacting Genes		18 interacting genes: ELAVL1 H2BC21 H3-4 HNRNPA1 HNRNPD NUP153 NUP214 NUP98 NXF1 PABPN1 RAN RANBP2 RGPD5 RPL23A RPL5 RPS7 SRP19 ULK2	30 interacting genes: APC CBFA2T3 CHMP5 CREBBP CSNK2A1 CYFIP1 EP300 HBE1 HDAC1 IPO5 KCNQ1 KPNB1 MUC2 NUP133 NUP155 NUP214 NUP62 NUP88 NXF1 PSMD13 RAE1 RCC1 RNH1 RRM1 SEC13 SLC22A18AS TNPO1 TNPO2 TPR UTRN
Entrez ID		3842	4928
HPRD ID		04210	03012
Ensembl ID		ENSG00000083312	ENSG00000110713
Uniprot IDs		A0A024RAM0 Q92973	P52948
PDB IDs		1QBK 2H4M 2OT8 2QMR 2Z5J 2Z5K 2Z5M 2Z5N 2Z5O 4FDD 4FQ3 4JLQ 4OO6 5J3V 5TQC 5YVG 5YVH 5YVI	1KO6 2Q5X 2Q5Y 3MMY 4OWR 5A9Q 6BZM
Enriched GO Terms of Interacting Partners?
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