KPNA5 and RBBP4

Number of citations of the paper that reports this interaction (PubMedID 26491019)
6

Data Source:
BioGRID (pull down)

		KPNA5	RBBP4
Description		karyopherin subunit alpha 5	RB binding protein 4, chromatin remodeling factor
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GO Annotations	Cellular Component	Nuclear Pore Nucleoplasm Cytosol	Nuclear Chromatin Nucleus Nucleoplasm Cytosol Sin3 Complex NuRD Complex NURF Complex Protein-containing Complex CAF-1 Complex ESC/E(Z) Complex
	Molecular Function	Protein Binding Nuclear Localization Sequence Binding Nuclear Import Signal Receptor Activity	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Protein Binding DNA-dependent ATPase Activity Nucleosomal DNA Binding Histone Binding Histone Deacetylase Binding
	Biological Process	NLS-bearing Protein Import Into Nucleus Modulation By Virus Of Host Process	DNA Replication DNA Replication-dependent Nucleosome Assembly DNA Replication-independent Nucleosome Assembly Chromatin Remodeling Cell Cycle Negative Regulation Of Cell Proliferation Chromatin Assembly CENP-A Containing Nucleosome Assembly ATP-dependent Chromatin Remodeling Negative Regulation Of Gene Expression, Epigenetic Regulation Of Cell Cycle Response To Growth Hormone Negative Regulation Of G0 To G1 Transition Regulation Of Signal Transduction By P53 Class Mediator
Pathways		ISG15 antiviral mechanism NS1 Mediated Effects on Host Pathways	Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 G0 and Early G1 Polo-like kinase mediated events PRC2 methylates histones and DNA Oxidative Stress Induced Senescence HDACs deacetylate histones PKMTs methylate histone lysines ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression Activation of anterior HOX genes in hindbrain development during early embryogenesis Deposition of new CENPA-containing nucleosomes at the centromere Regulation of TP53 Activity through Acetylation Cyclin E associated events during G1/S transition G1/S-Specific Transcription Cyclin A:Cdk2-associated events at S phase entry RNA Polymerase I Transcription Initiation Regulation of PTEN gene transcription Regulation of PTEN gene transcription Transcriptional Regulation by E2F6 HCMV Early Events
Drugs
Diseases
GWAS		Early cardiac repolarization ( 31600170) Telomere length ( 21460395)
Interacting Genes		14 interacting genes: ANP32A ANP32B ARNT BRMS1 CDKN1B EPAS1 FBXO7 HIF1A IL32 RBBP4 SPOP SPOPL TWIST1 WT1	62 interacting genes: AEBP2 ANXA7 ARMC12 BCL11A BCL11B BRCA1 BRMS1 BRMS1L CDKN1A CHAF1B CREB1 CREBBP CYTOR DHX30 ESR1 FOXK2 H1-1 H2AC20 H3-4 H3C1 H3C14 H4-16 H4C14 HAT1 HDAC1 HDAC2 HDAC3 HDAC4 HMOX2 ING1 KPNA3 KPNA5 LIN37 LIN52 LIN9 LMNA MBD2 MBD3 MBD3L2 MTA1 MTA2 MYBL2 NR2E3 PRDM16 RB1 RBBP7 RBP1 RPN1 RPN2 RYBP SALL4 SAP30 SIN3A SMN1 SP1 SP3 SPEN SUMO2 SUV39H1 TK1 TSSK3 XRCC6
Entrez ID		3841	5928
HPRD ID		05179	04232
Ensembl ID		ENSG00000196911	ENSG00000162521
Uniprot IDs		O15131	Q09028
PDB IDs		4U2X	2XU7 3GFC 4PBY 4PBZ 4PC0 4R7A 5FXY 5VTB 5WAI 5WAK 5XWR 5XXQ 5Y1U 6BW3 6BW4 6C23 6C24 6G16
Enriched GO Terms of Interacting Partners?
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