KPNB1 and PIAS4

  • Number of citations of the paper that reports this interaction (PubMedID 15383276)
  • 142
  • Data Source:
  • HPRD (two hybrid)

KPNB1

PIAS4

Description karyopherin subunit beta 1 protein inhibitor of activated STAT 4
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Asthma ( 31619474)
  • Body mass index ( 26426971)
  • Glycine levels ( 30837465)
  • HDL cholesterol ( 30275531)
  • HDL cholesterol levels ( 30698716)
  • HDL cholesterol levels in current drinkers ( 30698716)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels ( 30698716)
  • LDL cholesterol levels in current drinkers ( 30698716)
  • LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Medication use (HMG CoA reductase inhibitors) ( 31015401)
  • Multiple sclerosis ( 22190364)
  • Optic cup area ( 25631615)
  • Simvastatin-induced myopathy ( 31220337)
  • Triglyceride levels ( 30698716)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)
  • Chronic lymphocytic leukemia ( 28165464)
Interacting Genes 62 interacting genes: AMFR CD99 CHD3 CSE1L CSNK1A1 CUL4B ELAVL1 EPAS1 EXO1 FGFR1 H1-0 H1-2 IGFBP3 IGFBP5 IPO7 IPO8 ITCH KPNA1 KPNA2 KPNA3 KPNA4 KPNA6 LYST MESD MSL1 MTNR1A NFATC1 NFYA NUP153 NUP50 NUP54 NUP62 NUP98 NUTF2 PIAS4 PLCD1 PRKD3 PTHLH PTMA PTN PTPN2 RAN RANBP1 RANBP2 RPL5 RUNX1T1 SELENOS SENP2 SMAD2 SMAD3 SMN1 SMNDC1 SNUPN SOX9 SREBF2 SRY TAF3 TAF8 TERF1 TP53 TUBA1A UBR5 82 interacting genes: ACTN1 ALDOA AR AREL1 BARD1 BRCA1 BTAF1 CALCOCO2 CEBPD CHD3 CLK1 COIL ESRRA FTH1 GADD45G HDAC1 HDAC2 HNF4A HNRNPUL1 HTT IL15RA IMMT IMPDH2 IRF3 IRF7 KNTC1 KPNB1 KRT18 LAMP2 LEF1 LRIF1 MAGEH1 MAP1LC3A MDC1 MPRIP NEFL NR4A2 OAZ1 OPTN PARP1 PDE4A PDE4D PDE4DIP PHF11 PHGDH PIAS1 PIAS2 PLAG1 PRKCZ PRPF40A PTN RIF1 SATB1 SERBP1 SERPINA5 SETDB1 SH3GL3 SKIL SMAD1 SMAD2 SMAD3 SMAD4 SMAD7 SNAI2 SNIP1 SUMO1 SUMO2 SUMO3 TADA3 TCERG1 TICAM1 TOP2A TP53 TRIM27 TRIM32 UBE2I UBE2K VHL VIM ZHX1 ZNF512B ZW10
Entrez ID 3837 51588
HPRD ID 04114 06910
Ensembl ID ENSG00000108424 ENSG00000105229
Uniprot IDs B7Z752 Q14974 B3KMR4 Q8N2W9
PDB IDs 1F59 1IBR 1M5N 1O6O 1O6P 1QGK 1QGR 2P8Q 2Q5D 2QNA 3LWW 3W5K 6N88 6N89
Enriched GO Terms of Interacting Partners?
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