KLRC2 and FBP1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		KLRC2	FBP1
Description		killer cell lectin like receptor C2	fructose-bisphosphatase 1
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Receptor Complex	Nucleus Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding MHC Class I Protein Complex Binding Carbohydrate Binding Protein Antigen Binding	RNA Polymerase II Transcription Factor Binding Protein Binding AMP Binding Fructose 1,6-bisphosphate 1-phosphatase Activity Identical Protein Binding Metal Ion Binding Monosaccharide Binding
	Biological Process	Natural Killer Cell Mediated Immunity Cellular Defense Response Signal Transduction Innate Immune Response	Negative Regulation Of Transcription By RNA Polymerase II Sucrose Biosynthetic Process Fructose Metabolic Process Fructose 6-phosphate Metabolic Process Gluconeogenesis Regulation Of Gluconeogenesis Dephosphorylation Negative Regulation Of Cell Growth Fructose 1,6-bisphosphate Metabolic Process Cellular Response To Drug Negative Regulation Of Glycolytic Process Negative Regulation Of Ras Protein Signal Transduction Cellular Response To Magnesium Ion
Pathways		DAP12 interactions DAP12 signaling DAP12 signaling	Gluconeogenesis
Drugs			Adenosine monophosphate 2,5-Anhydroglucitol-1,6-Biphosphate {4-[3-(6,7-Diethoxy-Quinazolin-4-Ylamino)-Phenyl]-Thiazol-2-Yl}-Methanol Mdl-29951 Fructose-6-Phosphate MB-07803 Managlinat dialanetil N-[7-(3-AMINOPHENYL)-5-METHOXY-1,3-BENZOXAZOL-2-YL]-2,5-DICHLOROBENZENESULFONAMIDE 2,5-DICHLORO-N-(5-CHLORO-1,3-BENZOXAZOL-2-YL)BENZENESULFONAMIDE 2,5-DICHLORO-N-[5-METHOXY-7-(6-METHOXYPYRIDIN-3-YL)-1,3-BENZOXAZOL-2-YL]BENZENESULFONAMIDE 4-AMINO-N-[(2-SULFANYLETHYL)CARBAMOYL]BENZENESULFONAMIDE
Diseases			Fructose-1,6-bisphosphatase deficiency
GWAS		Blood protein levels ( 28240269) Composite immunoglobulin trait (IgA/IgG) ( 28628107) Neutrophil percentage of white cells ( 27863252)	Cerebrospinal fluid t-tau:AB1-42 ratio ( 28641921) Colorectal or endometrial cancer ( 26621817) Obesity-related traits ( 23251661)
Interacting Genes		3 interacting genes: FBP1 HLA-E KLRD1	20 interacting genes: ACTN1 ASCC2 ASL ATP5MF BCL2L1 BIN1 CSNK1E DYNC1I1 FXR2 HDAC6 HSPA8 KLRC2 LNX1 PCNX4 POT1 PRKN PTK2 RNF183 TERF1 TRIM28
Entrez ID		3822	2203
HPRD ID		04202	01973
Ensembl ID		ENSG00000205809	ENSG00000165140
Uniprot IDs		P26717	P09467 Q2TU34
PDB IDs		2L35	1FTA 2FHY 2FIE 2FIX 2JJK 2VT5 2WBB 2WBD 2Y5K 2Y5L 3A29 3KBZ 3KC0 3KC1 4MJO 5LDZ 5PZQ 5PZR 5PZS 5PZT 5PZU 5PZV 5PZW 5PZX 5PZY 5PZZ 5Q00 5Q01 5Q02 5Q03 5Q04 5Q05 5Q06 5Q07 5Q08 5Q09 5Q0A 5Q0B 5ZWK
Enriched GO Terms of Interacting Partners?
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