KCNJ12 and SNTB2

Number of citations of the paper that reports this interaction (PubMedID 15024025)
60

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, in vivo)

		KCNJ12	SNTB2
Description		potassium inwardly rectifying channel subfamily J member 12	syntrophin beta 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Intrinsic Component Of Membrane	Intracellular Cytoplasm Microtubule Focal Adhesion Dystrophin-associated Glycoprotein Complex Membrane Transport Vesicle Membrane Protein-containing Complex Synapse
	Molecular Function	Inward Rectifier Potassium Channel Activity Protein Binding	RNA Binding Actin Binding Structural Molecule Activity Protein Binding Calmodulin Binding
	Biological Process	Potassium Ion Transport Muscle Contraction Regulation Of Heart Contraction Regulation Of Ion Transmembrane Transport Protein Homotetramerization Cardiac Conduction Potassium Ion Import Across Plasma Membrane
Pathways		Activation of G protein gated Potassium channels Classical Kir channels Phase 4 - resting membrane potential Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs		Dofetilide Yohimbine
Diseases
GWAS		Body mass index ( 28892062 25673413) Height ( 20881960 31562340) Waist-hip ratio ( 25673412)	Body mass index ( 26426971) Logical memory (delayed recall) in normal cognition ( 29274321)
Interacting Genes		16 interacting genes: ABLIM1 APBA1 CASK DLG1 DLG2 DLG3 DLG4 DMD DTNA LIN7A LIN7B LIN7C PRKACA SNTA1 SNTB1 SNTB2	16 interacting genes: ABCA1 ADGRB1 ADRA1D DGKZ DMD DTNA ERBB4 KCNJ12 MAST1 MAST2 PTEN PTPRN SCN4A SCN5A UBC UTRN
Entrez ID		3768	6645
HPRD ID		09083	02491
Ensembl ID		ENSG00000184185	ENSG00000168807
Uniprot IDs		Q14500	A0A024R732 Q13425
PDB IDs			2VRF
Enriched GO Terms of Interacting Partners?
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