EIF6 and ZBTB26

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		EIF6	ZBTB26
Description		eukaryotic translation initiation factor 6	zinc finger and BTB domain containing 26
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Lamin Filament Nucleoplasm Nucleolus Cytoplasm Cytosol Preribosome, Large Subunit Precursor Extracellular Exosome	Cellular_component Nucleus
	Molecular Function	Translation Initiation Factor Activity Protein Binding Ribosome Binding Ribosomal Large Subunit Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Molecular_function DNA Binding Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Ribosomal Subunit Export From Nucleus Maturation Of 5.8S RRNA Maturation Of LSU-rRNA Regulation Of Glycolytic Process Translational Initiation Response To Insulin Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Mature Ribosome Assembly Regulation Of Fatty Acid Biosynthetic Process Regulation Of Megakaryocyte Differentiation Positive Regulation Of Translation Assembly Of Large Subunit Precursor Of Preribosome Regulation Of Reactive Oxygen Species Metabolic Process	Negative Regulation Of Transcription By RNA Polymerase II Biological_process
Pathways
Drugs		Copper
Diseases
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Height ( 18391951) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Body mass index ( 26426971)
Interacting Genes		37 interacting genes: ABCF1 ACAP3 ACTG1 AKT1S1 ALDH2 APP CEP126 CLEC4G CRELD1 CSNK2B DHX58 EIF2AK2 ENOX1 FUNDC2 GIT1 HIP1 HPF1 ITGB4 LRIF1 MRPS31 OAS3 OFD1 OS9 PDHA1 PLK1 POLA2 PRKCB PSME1 RACK1 RPL6 SEPTIN3 TK1 UPF3B USP33 WFS1 XRN2 ZBTB26	9 interacting genes: AXIN1 CYP2W1 EIF6 GIPC2 PBK SUMO1 SUMO1P1 UBE2I ZBTB6
Entrez ID		3692	57684
HPRD ID		04221	15692
Ensembl ID		ENSG00000242372	ENSG00000171448
Uniprot IDs		P56537	Q9HCK0
PDB IDs
Enriched GO Terms of Interacting Partners?
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