IRAK1 and NTRK3

  • Number of citations of the paper that reports this interaction (PubMedID 12034707)
  • 23
  • Data Source:
  • HPRD (in vivo)

IRAK1

NTRK3

Description interleukin 1 receptor associated kinase 1 neurotrophic receptor tyrosine kinase 3
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Amyotrophic lateral sclerosis (sporadic) ( 24529757)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Blood protein levels ( 30072576)
  • Diabetic peripheral neuropathy in type 2 diabetes ( 31127053)
  • Gaucher disease severity ( 22388998)
  • General risk tolerance (MTAG) ( 30643258)
Interacting Genes 49 interacting genes: AKT1 BCL10 BTK CCDC47 FADD H3-4 HRAS HSP90AA1 IKBKG IL1RAP IRAK1BP1 IRAK2 IRAK3 IRAK4 IRF4 IRF7 ITGAM JUN MAP3K7 MAPK14 MAPK8 MBP MYD88 NLRP12 NTRK3 OPTN PELI1 PELI2 PELI3 PPP3CB PRKCI PRKCZ RIPK2 SIGIRR SQSTM1 STAT3 STING1 SUMO1 TAB2 TICAM2 TIFA TIRAP TLR2 TLR4 TOLLIP TRAF4 TRAF6 TRIM32 YTHDC2 26 interacting genes: APP BEX3 DOK5 DYNLL1 ERBB2 FRS2 HEY1 HTR2A IRAK1 IRAK3 JUN KIDINS220 KPNA4 MAPK1 MAPK3 NELFB NGFR NSD1 NTF3 PLCG1 PTPN1 RASGRF1 SHC1 SHC2 SQSTM1 WDR13
Entrez ID 3654 4916
HPRD ID 02235 01870
Ensembl ID ENSG00000184216 ENSG00000140538
Uniprot IDs D3YTB5 P51617 B7Z7U4 O95193 Q16288 Q96CY4 X5D2R1 X5D7M5 X5DNW6
PDB IDs 6BFN 1WWC 3V5Q 4YMJ 6KZC 6KZD
Enriched GO Terms of Interacting Partners?
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