INSIG1 and HMGCR

  • Number of citations of the paper that reports this interaction (PubMedID 12535518)
  • 109
  • Data Source:
  • HPRD (in vivo)

INSIG1

HMGCR

Description insulin induced gene 1 3-hydroxy-3-methylglutaryl-CoA reductase
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Bladder cancer (smoking interaction) ( 24662972)
  • Diverticular disease ( 30177863)
  • Energy expenditure (24h) ( 28476931)
  • Formal thought disorder in schizophrenia ( 22648509)
  • Plasma anti-thyroglobulin and anti-thyroid peroxidase levels (bivariate analysis) ( 29678681)
  • Plasma anti-thyroglobulin levels ( 29678681)
  • Triiodothyronine levels and thyroxine levels ( 30843173)
Interacting Genes 7 interacting genes: ELOC HMGCR PSMA7 PSMC3 SCAP SREBF2 VCP 4 interacting genes: ARHGAP1 INSIG1 PRKACA STARD13
Entrez ID 3638 3156
HPRD ID 03633 00836
Ensembl ID ENSG00000186480 ENSG00000113161
Uniprot IDs A0A024RD68 A4D2M9 F5H6P3 O15503 A0A024RAP2 P04035
PDB IDs 4J81 1DQ8 1DQ9 1DQA 1HW8 1HW9 1HWI 1HWJ 1HWK 1HWL 2Q1L 2Q6B 2Q6C 2R4F 3BGL 3CCT 3CCW 3CCZ 3CD0 3CD5 3CD7 3CDA 3CDB
Enriched GO Terms of Interacting Partners?
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