IDO1 and PPP1R16A

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		IDO1	PPP1R16A
Description		indoleamine 2,3-dioxygenase 1	protein phosphatase 1 regulatory subunit 16A
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Smooth Muscle Contractile Fiber Stereocilium Bundle	Plasma Membrane
	Molecular Function	Tryptophan 2,3-dioxygenase Activity Electron Transfer Activity Heme Binding Indoleamine 2,3-dioxygenase Activity Metal Ion Binding	Protein Binding Protein Phosphatase Regulator Activity
	Biological Process	Immune System Process Cytokine Production Involved In Inflammatory Response Positive Regulation Of T Cell Tolerance Induction Positive Regulation Of Chronic Inflammatory Response Positive Regulation Of Type 2 Immune Response Tryptophan Catabolic Process Female Pregnancy Tryptophan Catabolic Process To Kynurenine Electron Transport Chain Response To Lipopolysaccharide Negative Regulation Of Interleukin-10 Production Positive Regulation Of Interleukin-12 Production Multicellular Organismal Response To Stress Kynurenic Acid Biosynthetic Process 'de Novo' NAD Biosynthetic Process From Tryptophan Swimming Behavior Negative Regulation Of T Cell Proliferation Regulation Of Activated T Cell Proliferation Negative Regulation Of T Cell Apoptotic Process Positive Regulation Of T Cell Apoptotic Process	Regulation Of Phosphoprotein Phosphatase Activity
Pathways		Tryptophan catabolism
Drugs		Nitric Oxide
Diseases
GWAS		Blood metabolite levels ( 24816252) Blood protein levels ( 29875488)	Age at first birth ( 27798627) Blood metabolite levels ( 26401656) Educational attainment ( 25201988) Height ( 28552196) Mean corpuscular hemoglobin concentration ( 27863252)
Interacting Genes		4 interacting genes: APP DDX24 PPP1R16A TERF2IP	22 interacting genes: CDH24 DDX27 FSD1 HGS HLA-E IDO1 LY6H LZTS2 PAPSS1 PBDC1 PHPT1 PPP1CA PPP1CB PPP1CC PUF60 RFLNB RGMA TFIP11 TLE5 TPP2 TRIP6 TXNRD1
Entrez ID		3620	84988
HPRD ID		00935	16454
Ensembl ID		ENSG00000131203	ENSG00000160972
Uniprot IDs		A0A348GSI3 P14902	Q96I34
PDB IDs		2D0T 2D0U 4PK5 4PK6 4U72 4U74 5EK2 5EK3 5EK4 5ETW 5WHR 5WMU 5WMV 5WMW 5WMX 5WN8 5XE1 6AZU 6AZV 6AZW 6CXU 6CXV 6DPQ 6DPR 6E35 6E40 6E41 6E42 6E43 6E44 6E45 6E46 6F0A 6MQ6 6O3I 6R63
Enriched GO Terms of Interacting Partners?
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