IL11RA and IL11

Number of citations of the paper that reports this interaction (PubMedID 7670098)
6

Data Source:
HPRD (in vitro, in vivo)

		IL11RA	IL11
Description		interleukin 11 receptor subunit alpha	interleukin 11
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Receptor Complex	Extracellular Region Extracellular Space Cytoplasm
	Molecular Function	Transmembrane Signaling Receptor Activity Cytokine Receptor Activity Interleukin-11 Receptor Activity Cytokine Binding Interleukin-11 Binding	Cytokine Activity Interleukin-11 Receptor Binding Protein Binding Growth Factor Activity
	Biological Process	Positive Regulation Of Cell Proliferation Cytokine-mediated Signaling Pathway Developmental Process Interleukin-11-mediated Signaling Pathway Head Development	Positive Regulation Of Cell Proliferation Cytokine-mediated Signaling Pathway B Cell Differentiation Megakaryocyte Differentiation Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of MAPK Cascade Fat Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Hormone Secretion Positive Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Complement-dependent Cytotoxicity Negative Regulation Of Endothelial Cell Apoptotic Process
Pathways		IL-6-type cytokine receptor ligand interactions	IL-6-type cytokine receptor ligand interactions
Drugs		Oprelvekin
Diseases
GWAS		Blood protein levels ( 30072576 29875488) CTACK levels ( 27989323)	Osteoarthritis (hip) ( 30374069) Response to antidepressants ( 20360315)
Interacting Genes		1 interacting genes: IL11	2 interacting genes: IL11RA MAGEA11
Entrez ID		3590	3589
HPRD ID		02965	00980
Ensembl ID		ENSG00000137070	ENSG00000095752
Uniprot IDs		Q14626 Q5VZ79	A8K3F7 P20809
PDB IDs			4MHL
Enriched GO Terms of Interacting Partners?
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