IKBKB and TFAP2C

  • Number of citations of the paper that reports this interaction (PubMedID 21988832)
  • 75
  • Data Source:
  • BioGRID (two hybrid)

IKBKB

TFAP2C

Description inhibitor of nuclear factor kappa B kinase subunit beta transcription factor AP-2 gamma
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blond vs. brown/black hair color ( 30531825)
  • Blood urea nitrogen levels ( 31152163)
  • Cerebrospinal P-tau181p levels ( 28247064)
  • Chronic obstructive pulmonary disease (moderate to severe) ( 24621683)
  • Cognitive decline rate in late mild cognitive impairment ( 26252872)
  • Ovarian cancer ( 30557369)
Interacting Genes 86 interacting genes: ACVR1 AKT1 AURKA CASP8 CCAR2 CDC37 CFLAR CHUK COPS3 COPS4 CSF2RA CSF2RB CTNNB1 CUEDC2 E2F4 EIF2AK2 EIF2AK3 ELP1 FAF1 FANCA FOXO3 GLI1 HSP90AA1 HSP90AB1 HTT IKBKG IRS1 JUN KLHL21 MAP3K1 MAP3K11 MAP3K13 MAP3K14 MAP3K3 MAP3K7 MAVS MTDH NAA20 NCOA3 NEDD4L NFKB1 NFKB2 NFKBIA NFKBIB NR2C2 PEBP1 PELI1 PLK1 PPARG PPM1B PPP2R3C PRKCA PRKCB PRKCD PRKCE PRKCQ PRKCZ PRKDC RELA RICTOR RIPK1 ROCK1 SASH1 SRC STAP2 TAB2 TANK TBK1 TFAP2C TGFBR1 TNFAIP3 TNFRSF1A TP53 TP73 TRAF1 TRAF2 TRAF3IP2 TRIM21 TRIM27 TRPC4AP TSC1 TWIST1 UBB UBC VHL YWHAB 12 interacting genes: CCNG1 CITED1 CITED2 CITED4 ERBB4 GPR22 IKBKB NR1I2 TP53 UBE2I WWOX ZFAND4
Entrez ID 3551 7022
HPRD ID 04462 03361
Ensembl ID ENSG00000104365 ENSG00000087510
Uniprot IDs O14920 Q92754
PDB IDs 3BRT 3BRV 4E3C 4KIK
Enriched GO Terms of Interacting Partners?
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