IGFBP3 and MMP3

  • Number of citations of the paper that reports this interaction (PubMedID 7523391)
  • 40
  • Data Source:
  • HPRD (in vitro)

IGFBP3

MMP3

Description insulin like growth factor binding protein 3 matrix metallopeptidase 3
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease ( 22832961)
  • Blood protein levels ( 30072576 28240269)
  • Blood protein levels in cardiovascular risk ( 28369058)
  • Cerebrospinal fluid levels of Alzheimer's disease-related proteins ( 25340798)
  • Peripheral artery disease ( 31285632)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)
Interacting Genes 29 interacting genes: ADAM12 CAV1 CD44 COL1A1 CSNK2A1 CTSD CTSG CTSL F2 FN1 GPI GTF3C1 IGF1 IGF1R IGF2 IGFALS KLK3 KLKB1 KPNB1 LTBP1 MMP1 MMP2 MMP3 PAPPA2 PLG POLA2 PPARG RXRA TF 19 interacting genes: ACAN BCAN CCL13 CCL2 CCL7 CCL8 DCN HAPLN1 IGFBP3 MEOX2 MMP14 PLG SERPINE1 SPOCK1 SPOCK3 SPP1 TIMP1 TIMP3 TNFSF11
Entrez ID 3486 4314
HPRD ID 00899 01703
Ensembl ID ENSG00000146674 ENSG00000149968
Uniprot IDs B3KPF0 P17936 P08254
PDB IDs 1B3D 1B8Y 1BIW 1BM6 1BQO 1C3I 1C8T 1CAQ 1CIZ 1CQR 1D5J 1D7X 1D8F 1D8M 1G05 1G49 1G4K 1HFS 1HY7 1M1W 1OO9 1QIA 1QIC 1SLM 1SLN 1UEA 1UMS 1UMT 1USN 2D1O 2JNP 2JT5 2JT6 2SRT 2USN 3OHL 3OHO 3USN 4DPE 4G9L 4JA1 6MAV 6N9D
Enriched GO Terms of Interacting Partners?
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