IGF2R and PLIN3

Number of citations of the paper that reports this interaction (PubMedID 9590177)
106

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		IGF2R	PLIN3
Description		insulin like growth factor 2 receptor	perilipin 3
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Lumen Lysosomal Membrane Endosome Early Endosome Late Endosome Golgi Apparatus Trans-Golgi Network Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Cell Surface Membrane Clathrin Coat Transport Vesicle Endocytic Vesicle Trans-Golgi Network Transport Vesicle Clathrin-coated Vesicle Membrane Secretory Granule Membrane Trans-Golgi Network Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome	Cytoplasm Endosome Golgi Apparatus Lipid Droplet Cytosol Endosome Membrane Membrane Transport Vesicle
	Molecular Function	G-protein Alpha-subunit Binding Retinoic Acid Binding Insulin-like Growth Factor-activated Receptor Activity Protein Binding Insulin-like Growth Factor Binding Mannose Binding Enzyme Binding Insulin-like Growth Factor II Binding Signaling Receptor Activity Identical Protein Binding Phosphoprotein Binding	Protein Binding Cadherin Binding
	Biological Process	Liver Development Receptor-mediated Endocytosis Lysosomal Transport Signal Transduction G Protein-coupled Receptor Signaling Pathway Spermatogenesis Post-embryonic Development Animal Organ Regeneration Response To Retinoic Acid Positive Regulation Of Apoptotic Process Neutrophil Degranulation Positive Regulation By Host Of Viral Process Insulin-like Growth Factor Receptor Signaling Pathway Membrane Organization	Vesicle-mediated Transport
Pathways		Golgi Associated Vesicle Biogenesis Neutrophil degranulation Retrograde transport at the Trans-Golgi-Network Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis	Triglyceride catabolism Retrograde transport at the Trans-Golgi-Network Lipophagy Chaperone Mediated Autophagy Late endosomal microautophagy
Drugs		Mecasermin alpha-D-mannose 6-phosphate Cerliponase alfa	Idursulfase Galsulfase
Diseases		Hepatocellular carcinoma
GWAS		Blood protein levels ( 30072576 29875488 28240269) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Brain lesion load ( 19010793) Coronary artery disease ( 29212778) Lipoprotein (a) levels ( 26377243) Periodontitis (CDC/AAP) ( 24024966) Serum metabolite concentrations in chronic kidney disease ( 29545352)	Basal cell carcinoma ( 27539887) Lung cancer in ever smokers ( 28604730) Visceral fat ( 30942860)
Interacting Genes		14 interacting genes: AGA ATXN1 CREG1 CSNK2A1 CTSD GGA1 GGA2 GGA3 GZMB IGF2 PACS1 PLAU PLAUR PLIN3	9 interacting genes: APP CMTM5 IGF2R M6PR MAX RAB9A SMAD2 SPART TBPL1
Entrez ID		3482	10226
HPRD ID		00928	04080
Ensembl ID		ENSG00000197081	ENSG00000105355
Uniprot IDs		P11717	A0A140VJN8 O60664
PDB IDs		1E6F 1GP0 1GP3 1GQB 1JPL 1JWG 1LF8 2CNJ 2L29 2L2A 2M68 2M6T 2V5N 2V5O 2V5P 5IEI 6N5X 6N5Y
Enriched GO Terms of Interacting Partners?
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