IFI16 and TP53BP1

  • Number of citations of the paper that reports this interaction (PubMedID 8910340)
  • 19
  • Data Source:
  • HPRD (two hybrid, in vitro, in vivo)

IFI16

TP53BP1

Description interferon gamma inducible protein 16 tumor protein p53 binding protein 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood protein levels ( 29875488)
  • C-reactive protein ( 22939635)
  • Celiac disease or Rheumatoid arthritis ( 21383967)
  • Neutrophil count in HIV-infection ( 25884002)
  • Obesity-related traits ( 23251661)
  • Periodontal disease-related phenotype (Socransky) ( 26962152)
  • Antibody level in response to infection ( 25758998)
  • Cardiometabolic and hematological traits ( 27668658)
  • HDL cholesterol levels ( 30698716)
  • HDL cholesterol levels in current drinkers ( 30698716)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Lipoprotein phospholipase A2 activity in cardiovascular disease ( 28753643)
  • Lung cancer in ever smokers ( 28604730)
  • Triglyceride levels ( 30698716)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Triglycerides ( 27036123)
Interacting Genes 11 interacting genes: APP AR AURKA BRCA1 CSNK2A1 ID1 ID2 ID3 TP53 TP53BP1 TPR 42 interacting genes: ARAP1 ATM BLM BRCA1 BRCA2 CCNB1 CDK1 CHEK1 CRB2 DCLRE1A DCLRE1C DYNLL1 E2F1 EP300 GALNTL5 H2AX H4-16 H4C14 IFI16 KAT8 KDM1A LIG4 MDC1 MEOX2 NCOA3 NEK1 NFKB1 NUDT16L1 PAXIP1 PCNT RAD18 RAD50 RAD51 RBL1 RBL2 RELA SPAG9 SUMO2 TFDP1 TP53 USP28 VAC14
Entrez ID 3428 7158
HPRD ID 00969 05569
Ensembl ID ENSG00000163565 ENSG00000067369
Uniprot IDs Q16666 A6NNK5 Q12888
PDB IDs 2OQ0 3B6Y 3RLN 3RLO 3RNU 4QGU 1GZH 1KZY 1XNI 2G3R 2IG0 2LVM 2MWO 2MWP 3LGF 3LGL 3LH0 4CRI 4RG2 4X34 5ECG 5J26 5KGF 5Z78 5ZCJ 6CO1 6CO2 6IU7 6IUA 6MXX 6MXY 6MXZ 6MY0 6RML 6RMM 6UPT
Enriched GO Terms of Interacting Partners?
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