LINC01139 and GPNMB

Number of citations of the paper that reports this interaction (PubMedID 26751287)
112

Data Source:
BioGRID (unspecified method)

		LINC01139	GPNMB
Description		long intergenic non-protein coding RNA 1139	glycoprotein nmb
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Early Endosome Membrane Melanosome Membrane
	Molecular Function		Integrin Binding Protein Binding Heparin Binding Chemoattractant Activity Syndecan Binding Receptor Ligand Activity
	Biological Process		Osteoblast Differentiation Negative Regulation Of Cytokine Production Positive Regulation Of Protein Phosphorylation Cell Adhesion Signal Transduction Cell-cell Signaling Negative Regulation Of Cell Proliferation Bone Mineralization Positive Regulation Of Cell Migration Positive Regulation Of Protein Autophosphorylation Negative Regulation Of Tumor Necrosis Factor Production Regulation Of Tissue Remodeling Negative Regulation Of T Cell Proliferation Regulation Of Angiogenesis Negative Regulation Of T Cell Activation Positive Chemotaxis Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Neuron Death Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways			PTK6 promotes HIF1A stabilization
Drugs
Diseases
GWAS			Blood protein levels ( 30072576 29875488 28240269) Iron status biomarkers (transferrin saturation) ( 28334935) Parkinson's disease ( 25064009 28892059) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
Interacting Genes		5 interacting genes: EGFR GPNMB HIF1A LRRK2 PTK6	4 interacting genes: EGFR ITSN2 LINC01139 SMAD4
Entrez ID		339535	10457
HPRD ID			05081
Ensembl ID		ENSG00000215808	ENSG00000136235
Uniprot IDs			A0A024RA55 Q14956 Q96F58
PDB IDs
Enriched GO Terms of Interacting Partners?
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